Chibby Homolog 1 (Drosophila) 蛋白 (CBY1)

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. 再加上,我们可以发CBY1 抗体 (39)CBY1 试剂盒 (8)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
CBY1 25776 Q9Y3M2
CBY1 73739 Q9D1C2
CBY1 246768 Q8K4I6
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Showing 8 out of 11 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$5,465.26
详细
大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$5,465.26
详细
HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$414.29
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大肠杆菌(E. Coli) 非结合性 SDS-PAGE analysis of Human CBY1 Protein. 100 μg Log in to see 11至18个工作日
$540.11
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大肠杆菌(E. Coli) 小鼠 非结合性 SDS-PAGE analysis of Mouse CBY1 Protein. 100 μg Log in to see 11至18个工作日
$568.54
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酵母菌 大鼠 His tag   1 mg Log in to see 60至71个工作日
$2,258.67
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酵母菌 Cow His tag   1 mg Log in to see 60至71个工作日
$2,258.67
详细

CBY1 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, , ,
Mouse (Murine)

Rat (Rattus)

更多Chibby Homolog 1 (Drosophila) (CBY1)互动伙伴

Xenopus laevis Chibby Homolog 1 (Drosophila) (CBY1) interaction partners

  1. Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression.

Human Chibby Homolog 1 (Drosophila) (CBY1) interaction partners

  1. FAM92 proteins interact with Cby1 to promote ciliogenesis via regulation of membrane-remodeling processes.

  2. chronic Cby1 knockdown in colon cancer cells may counteract tumor progression by promoting the mesenchymal-to-epithelial transition process.

  3. Cby's C-terminal domain alone binds to TC-1 with significantly greater affinity compared to full-length Cby, implying that target binding of the coiled-coil domain is affected by the flanking disordered regions.

  4. CBY1 downregulation in CML (显示 BCR 蛋白) comes from reduced protein stability when bound to 14-3-3sigma adapter protein (显示 TOLLIP 蛋白). Dissociation raises CBY1 protein levels by enhancing its stability. The ubiquitin proteasome system reduces 14-3-3sigma-bound CBY1 stability by SUMOylation.

  5. Results show the hypermethylation of CBY1 and BCL2 (显示 BCL2 蛋白)-like11 promoters proceeding from DNMT1 (显示 DNMT1 蛋白) is a crucial component of their reduced expression, but it is not directly involved in chronic myeloid leukemia (显示 BCL11A 蛋白) resistance to imatinib.

  6. Study showed that expression of Cby protein was strongly downregulated in laryngeal squamous cell carcinoma (LSCC) tumor tissues in comparison to normal laryngeal mucosa samples.

  7. the impact of BCR (显示 BCR 蛋白)-ABL1 (显示 ABL1 蛋白) on Chibby1, a beta (显示 SUCLA2 蛋白) catenin (显示 CTNNB1 蛋白) antagonist involved in cell differentiation and transformation

  8. Stable expression of CBY1 drives beta catenin (显示 CTNNB1 蛋白) cytoplasmatic translocation and impairs beta catenin (显示 CTNNB1 蛋白) signaling in BCR-ABL (显示 ABL1 蛋白) + cells.

  9. Results from the association analysis suggest that common variation in CBY is not a cause for obesity in the Belgian population.

  10. C-terminal polycystin-2 (显示 PKD2 蛋白) influences the interaction with PIGEA14

Mouse (Murine) Chibby Homolog 1 (Drosophila) (CBY1) interaction partners

  1. FAM92 proteins interact with Cby1 to promote ciliogenesis via regulation of membrane-remodeling processes.

  2. Cby1 is required for efficient recruitment of Ahi1 (显示 AHI1 蛋白), providing a possible molecular mechanism for the ciliogenesis defect in Cby1(-/-) cells.

蛋白简介CBY1

蛋白简介

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CBY1

  • chibby homolog 1 S homeolog (cby1.S)
  • chibby homolog 1 (cby1)
  • chibby family member 1, beta catenin antagonist (CBY1)
  • chibby family member 1, beta catenin antagonist (Cby1)
  • 1110014P06Rik 蛋白
  • arb1 蛋白
  • C22orf2 蛋白
  • CBY 蛋白
  • chibby 蛋白
  • HS508I15A 蛋白
  • Pgea1 蛋白
  • PGEA14 蛋白
  • PIGEA-14 蛋白
  • PIGEA14 蛋白

Protein level used designations for CBY1

chibby homolog 1 , leucine-rich protein , ARPP-binding protein , PKD2 interactor, Golgi and endoplasmic reticulum-associated 1 , PKD2 interactor, golgi and endoplasmic reticulum associated 1 , coiled-coil protein PIGEA-14 , cytosolic leucine-rich protein , polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa , protein chibby homolog 1 , PIGEA-14

GENE ID SPECIES
398327 Xenopus laevis
549007 Xenopus (Silurana) tropicalis
25776 Homo sapiens
73739 Mus musculus
246768 Rattus norvegicus
282859 Bos taurus
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