CCAR2 蛋白
(Cell Cycle and Apoptosis Regulator 2 (CCAR2))
Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity.
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custom-made
CCAR2
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
CCAR2
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for CCAR2 蛋白
cell cycle and apoptosis regulator 2 (CCAR2) 蛋白cell cycle activator and apoptosis regulator 2 (Ccar2) 蛋白
cell cycle and apoptosis regulator 2 (Ccar2) 蛋白
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