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Dual Specificity Phosphatase 3 抗体

(Dual Specificity Phosphatase 3 (DUSP3))
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1. [provided by RefSeq, Jul 2008].
Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) 抗体 Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) 抗体 Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) 抗体 (ABIN7426586)

DUSP3 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal 2# unconjugated

Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) 抗体 Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) 抗体 Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) 抗体 (ABIN560661)

DUSP3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5B7 unconjugated

Dual Specificity Phosphatase 3 (DUSP3) 抗体 Dual Specificity Phosphatase 3 (DUSP3) 抗体 Dual Specificity Phosphatase 3 (DUSP3) 抗体 (ABIN2856654)

DUSP3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Dual Specificity Phosphatase 3 抗体 by 适用

Find Dual Specificity Phosphatase 3 抗体 for a variety of species such as anti-Human Dual Specificity Phosphatase 3, anti-Mouse Dual Specificity Phosphatase 3, anti-Rat Dual Specificity Phosphatase 3. The species listed below are among those available. Click on a link to go to the corresponding products.

Dual Specificity Phosphatase 3 抗体 by 应用范围

Find Dual Specificity Phosphatase 3 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Dual Specificity Phosphatase 3 抗体 by 抗原表位

Find Dual Specificity Phosphatase 3 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Dual Specificity Phosphatase 3 抗体 by 克隆形成能力

Find available monoclonal or polyclonal Dual Specificity Phosphatase 3 抗体. Click on a link to go to the corresponding products.

Dual Specificity Phosphatase 3 抗体 by 克隆

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Dual Specificity Phosphatase 3 抗体 by 标记

Find Dual Specificity Phosphatase 3 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Dual Specificity Phosphatase 3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (4)
Cat. No. ABIN7426586
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN560661
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN2856654
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN392924
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (2)
Cat. No. ABIN7437629
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (2)
Cat. No. ABIN3187762
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6261383
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
Cat. No. ABIN392859
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7185660
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7150769
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN7255902
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (1)
Cat. No. ABIN515103
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6139873
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN360840
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
Cat. No. ABIN716321
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Dual Specificity Phosphatase 3 抗体

Wang, Yeh, Chou, Yang, Fu, Chen, Cheng, Huang, Liu, Huang, Chen: "Vaccinia H1-related phosphatase is a phosphatase of ErbB receptors and is down-regulated in non-small cell lung cancer." in: The Journal of biological chemistry, Vol. 286, Issue 12, pp. 10177-84, (2011) (PubMed).

Tabernero, Aricescu, Jones, Szedlacsek: "Protein tyrosine phosphatases: structure-function relationships." in: The FEBS journal, Vol. 275, Issue 5, pp. 867-82, (2008) (PubMed).

Alonso, Rahmouni, Williams, van Stipdonk, Jaroszewski, Godzik, Abraham, Schoenberger, Mustelin: "Tyrosine phosphorylation of VHR phosphatase by ZAP-70." in: Nature immunology, Vol. 4, Issue 1, pp. 44-8, (2002) (PubMed).

Alonso, Saxena, Williams, Mustelin: "Inhibitory role for dual specificity phosphatase VHR in T cell antigen receptor and CD28-induced Erk and Jnk activation." in: The Journal of biological chemistry, Vol. 276, Issue 7, pp. 4766-71, (2001) (PubMed).

Yuvaniyama, Denu, Dixon, Saper: "Crystal structure of the dual specificity protein phosphatase VHR." in: Science (New York, N.Y.), Vol. 272, Issue 5266, pp. 1328-31, (1996) (PubMed).

Aroca, Bottaro, Ishibashi, Aaronson, Santos: "Human dual specificity phosphatase VHR activates maturation promotion factor and triggers meiotic maturation in Xenopus oocytes." in: The Journal of biological chemistry, Vol. 270, Issue 23, pp. 14229-34, (1995) (PubMed).

Ishibashi, Bottaro, Chan, Miki, Aaronson: "Expression cloning of a human dual-specificity phosphatase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 24, pp. 12170-4, (1993) (PubMed).

Aliases for Dual Specificity Phosphatase 3 抗体

dual specificity phosphatase 3 (DUSP3) 抗体
dual specificity phosphatase 3b (dusp3b) 抗体
dual specificity phosphatase 3 (Dusp3) 抗体
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) (Dusp3) 抗体
2210015O03Rik 抗体
5031436O03Rik 抗体
dusp3 抗体
RGD1560049 抗体
si:bz18k17.3 抗体
si:rp71-18k17.3 抗体
T-DSP11 抗体
VHR 抗体
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