DUSP1 抗体
(Dual Specificity Phosphatase 1 (DUSP1))
The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| DUSP1 抗体 (C-Term) | 人 | 山羊 Polyclonal |
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| DUSP1 抗体 (AA 151-250) | 人 | 兔 Polyclonal |
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| DUSP1 抗体 (Ser296, Ser318) | 人 | 兔 Polyclonal |
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| DUSP1 抗体 (AA 305-367) | 人 | 小鼠 Monoclonal |
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| DUSP1 抗体 (AA 305-367) | 人 | 小鼠 Monoclonal |
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| DUSP1 抗体 (C-Term) | 人, 大鼠, 犬 | 兔 Polyclonal |
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| DUSP1 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| DUSP1 抗体 (pSer296, pSer318) | 人 | 兔 Polyclonal |
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| DUSP1 抗体 (Ser31) | 人 | 兔 Polyclonal |
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| DUSP1 抗体 (AA 151-250) (AbBy Fluor® 488) | 人 | 兔 Polyclonal |
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| DUSP1 抗体 (AA 125-236) | 人 | 兔 Polyclonal |
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| DUSP1 抗体 (AA 305-367) | 人 | 小鼠 Polyclonal |
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|
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| DUSP1 抗体 (AA 151-250) (AbBy Fluor® 647) | 人 | 兔 Polyclonal |
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| DUSP1 抗体 (AA 151-250) (AbBy Fluor® 594) | 人 | 兔 Polyclonal |
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| DUSP1 抗体 (AA 151-250) (Biotin) | 人 | 兔 Polyclonal |
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| DUSP1 抗体 (AA 151-250) (Cy3) | 人 | 兔 Polyclonal |
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| DUSP1 抗体 (AA 151-250) (AbBy Fluor® 555) | 人 | 兔 Polyclonal |
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| DUSP1 抗体 (AA 151-250) (Cy5.5) | 人 | 兔 Polyclonal |
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| DUSP1 抗体 (AA 151-250) (Cy7) | 人 | 兔 Polyclonal |
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| DUSP1 抗体 (AA 151-250) (AbBy Fluor® 680) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 质量等级
- Verified
- 适用
- 人
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
3 references - 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 151-250
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Ser296, Ser318
Primary Antibody
- ELISA (ELISA: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 3A9
- 标记
- unconjugated
- 抗体亚型
- IgG2b
- 抗原表位
- AA 305-367
Primary Antibody
- ELISA (ELISA: 有验证图片)
- PLA (Proximity Ligation Assay: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4H7
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 305-367
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- 适用
- 人, 大鼠, 犬
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 87-101, C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer296, pSer318
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Ser31
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 488
- 抗体亚型
- IgG
- 抗原表位
- AA 151-250
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 125-236
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 305-367
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 647
- 抗体亚型
- IgG
- 抗原表位
- AA 151-250
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 594
- 抗体亚型
- IgG
- 抗原表位
- AA 151-250
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 151-250
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- AA 151-250
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 555
- 抗体亚型
- IgG
- 抗原表位
- AA 151-250
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5.5
- 抗体亚型
- IgG
- 抗原表位
- AA 151-250
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy7
- 抗体亚型
- IgG
- 抗原表位
- AA 151-250
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 680
- 抗体亚型
- IgG
- 抗原表位
- AA 151-250
Latest Publications for our DUSP1 抗体
: "Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity." in: Frontiers in pharmacology, Vol. 8, pp. 653, (2017) (PubMed).
: "Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis." in: Oncotarget, Vol. 7, Issue 2, pp. 2009-21, (2016) (PubMed).
: "Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells." in: International journal of molecular sciences, Vol. 17, Issue 8, (2016) (PubMed).
: "MAP kinase phosphatase DUSP1 is overexpressed in human obese and modulated by physical activity." in: American journal of physiology. Endocrinology and metabolism, pp. ajpendo.00577.2013, (2014) (PubMed).
: "Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival." in: The Journal of biological chemistry, Vol. 280, Issue 6, pp. 4117-24, (2005) (PubMed).
: "Role of CL-100, a dual specificity phosphatase, in thrombin-induced endothelial cell activation." in: The Journal of biological chemistry, Vol. 279, Issue 45, pp. 46678-85, (2004) (PubMed).
: "Evidence that mitogen-activated protein kinase phosphatase-1 induction by proteasome inhibitors plays an antiapoptotic role." in: Molecular pharmacology, Vol. 66, Issue 6, pp. 1478-90, (2004) (PubMed).
: "The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts." in: Oncogene, Vol. 8, Issue 7, pp. 2015-20, (1993) (PubMed).
: "Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis." in: Oncotarget, Vol. 7, Issue 2, pp. 2009-21, (2016) (PubMed).
: "Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells." in: International journal of molecular sciences, Vol. 17, Issue 8, (2016) (PubMed).
: "MAP kinase phosphatase DUSP1 is overexpressed in human obese and modulated by physical activity." in: American journal of physiology. Endocrinology and metabolism, pp. ajpendo.00577.2013, (2014) (PubMed).
: "Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival." in: The Journal of biological chemistry, Vol. 280, Issue 6, pp. 4117-24, (2005) (PubMed).
: "Role of CL-100, a dual specificity phosphatase, in thrombin-induced endothelial cell activation." in: The Journal of biological chemistry, Vol. 279, Issue 45, pp. 46678-85, (2004) (PubMed).
: "Evidence that mitogen-activated protein kinase phosphatase-1 induction by proteasome inhibitors plays an antiapoptotic role." in: Molecular pharmacology, Vol. 66, Issue 6, pp. 1478-90, (2004) (PubMed).
: "The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts." in: Oncogene, Vol. 8, Issue 7, pp. 2015-20, (1993) (PubMed).
Aliases for DUSP1 抗体
dual specificity phosphatase 1 (DUSP1) 抗体dual specificity phosphatase 1 (Dusp1) 抗体
dual specificity phosphatase 1 (dusp1) 抗体
dual specificity phosphatase 1 S homeolog (dusp1.S) 抗体
3CH134 抗体
cb269 抗体
CL100 抗体
DUSP1 抗体
erp 抗体
HVH1 抗体
id:ibd2586 抗体
MKP-1 抗体
mkp-1 抗体
MKP1 抗体
Mkp1 抗体
PTPN10 抗体
Ptpn16 抗体
sb:cb269 抗体
U19515 抗体
wu:fd19g02 抗体
wu:fe50g09 抗体
XCL100 抗体
zgc:55920 抗体
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