anti-大鼠 Phospholipase C gamma 2 抗体 for Enzyme Immunoassay

Recommended Phospholipase C gamma 2 Antibody (supplied by: Log in to see )

抗原
Phospholipase C gamma 2 (PLCG2) 抗体
  • PLCgamma2
  • Plcg-2
  • APLAID
  • FCAS3
  • phospholipase C, gamma 2
  • phospholipase C gamma 2
  • phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • Plcg2
  • PLCG2
适用
人, 小鼠, 大鼠
310
152
143
12
4
4
4
4
3
1
宿主

212
98
克隆类型
多克隆
标记
This Phospholipase C gamma 2 antibody is un-conjugated
9
9
8
8
8
5
5
5
5
5
5
5
5
5
5
3
3
3
3
3
3
3
3
3
3
3
3
应用范围
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
221
108
86
59
51
45
40
27
16
4
3
3
2
Supplier
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产品编号 ABIN271905
$ 390.50
加上运输费 $45.00

General

抗原 Phospholipase C gamma 2 (PLCG2) 抗体
适用 人, 小鼠, 大鼠
(310), (152), (143), (12), (4), (4), (4), (4), (3), (1)
宿主
(212), (98)
克隆类型
多克隆
标记 This Phospholipase C gamma 2 antibody is un-conjugated
(9), (9), (8), (8), (8), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
应用范围 Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(221), (108), (86), (59), (51), (45), (40), (27), (16), (4), (3), (3), (2)
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Phospholipase C gamma 2抗体详情

Phospholipase C gamma 2目标详情 使用细节 贮存及处理 图像
特异性 This antibody detects endogenous levels of PLCG2 protein. (region surrounding Arg747)
交叉反应 (详细) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
纯化方法 Affinity Chromatography using epitope-specific immunogen

Phospholipase C gamma 2目标详情

Phospholipase C gamma 2抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 PLCG2 (PLCG2 Antibody 摘要)
背景 Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. There are many mammalian PLC isozymes, including PLC β1, PLC β2, PLC β3, PLC β4, PLCγ1, PLCγ2, PLC δ1, PLC δ2 and PLCe. PLCδ exists as four different isoforms. PLC δ1, a calcium signal amplifier, is activated by an atypical GTP-binding protein. In addition, PLC δ1 is an effector for GTP-binding protein transglutaminase II-mediated oxytocin receptor and α1B-adrenoreceptor signaling. Mouse PLC δ1 is highly expressed in brain, heart, lung and testis. PLC δ is abnormally accumulated in autopsied brains with Alzheimer's disease (AD), suggesting that it may play a role in the pathology of AD. PLC δ2 is markedly expressed in type II intestinal metaplasia and in the adenocarcinoma. When PLC δ2 is expressed in type I intestinal metaplasia, the metaplasia is generally considered benignant, yet evolves toward neoplastic transformation. Thus, PLC δ2 expression may be a possible marker of gastric malignant transformation.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-2, PLC-IV, PLC-gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, Phospholipase C-gamma-2
分子量 approx. 148 kDa
基因ID 5336
NCBI登录号 NP_002652
UniProt P16885
途径 RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling

使用细节

Phospholipase C gamma 2抗体详情 Phospholipase C gamma 2目标详情 贮存及处理 图像 回页首
应用备注 ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用

贮存及处理

Phospholipase C gamma 2抗体详情 Phospholipase C gamma 2目标详情 使用细节 图像 回页首
浓度 1.0 mg/mL
缓冲液 Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

图像

Phospholipase C gamma 2抗体详情 Phospholipase C gamma 2目标详情 使用细节 贮存及处理 回页首
厂商提供的图像
 image for anti-Phospholipase C gamma 2 (PLCG2) antibody (ABIN271905) anti-Phospholipase C gamma 2 (PLCG2) antibody
 image for anti-Phospholipase C gamma 2 (PLCG2) antibody (ABIN271905) anti-Phospholipase C gamma 2 (PLCG2) antibody (Image 2)