Phospholipase C gamma 2 抗体 (pTyr1217)
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Quick Overview for Phospholipase C gamma 2 抗体 (pTyr1217) (ABIN1531375)
抗原
See all Phospholipase C gamma 2 (PLCG2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1186-1235, pTyr1217
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原理
- PLC γ2 (phospho Tyr1217) Antibody
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特异性
- Phospho-PLC γ2 (Y1217) Polyclonal Antibody detects endogenous levels of PLC γ2 protein only when phosphorylated at Y1217.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PLCG2 around the phosphorylation site of Tyr1217. AA range:1186-1235
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亚型
- IgG
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anti-Phospholipase C gamma 2 (PLCG2) (AA 826-985) antibody
PLCG2 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2D9E8 unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 1-300) antibodyPLCG2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 1201-1258) antibodyPLCG2 适用: 人 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (pTyr753) antibodyPLCG2 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3A8B6 unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 826-985) antibodyPLCG2 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 1E10C11 unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 1-1265) antibodyPLCG2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 1-1265) antibodyPLCG2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 1-1265) antibodyPLCG2 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (C-Term) antibodyPLCG2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal AFfirm8557 unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (pTyr753) antibodyPLCG2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Phospholipase C gamma 2 (PLCG2)
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别名
- PLCG2
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背景
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Synonyms: PLCG2, 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, PLC-IV, Phospholipase C-gamma-2, PLC-gamma-2
Background: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014],
Gene Name: PLCG2
Protein Name: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
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分子量
- 147 kDa
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基因ID
- 5336
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OMIM
- 600220
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UniProt
- P16885
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途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
抗原
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