anti-小鼠 ERBB3 抗体 for Immunoprecipitation

Recommended ERBB3 Antibody (supplied by: Log in to see )

抗原
V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) 抗体
  • ERBB3
  • ErbB-3
  • HER3
  • LCCS2
  • MDA-BF-1
  • c-erbB-3
  • c-erbB3
  • erbB3-S
  • p180-ErbB3
  • p45-sErbB3
  • p85-sErbB3
  • nuc-ErbB3
  • C76256
  • Erbb-3
  • Erbb3r
  • Her3
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
  • ERBB3
  • Erbb3
抗原表位
AA 1283-1323, C-Term
41
40
27
22
21
19
15
15
15
15
15
14
13
12
10
10
10
9
8
7
7
5
5
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠, 大鼠
517
197
172
14
7
6
6
4
3
3
3
2
2
2
2
1
1
宿主

302
213
27
3
克隆类型
多克隆
标记
This ERBB3 antibody is un-conjugated
14
11
11
11
10
10
7
7
7
6
5
5
5
5
5
5
5
5
4
4
3
3
3
3
3
3
3
3
2
应用范围
Immunoprecipitation (IP), Western Blotting (WB)
311
194
148
109
107
84
67
56
10
8
8
8
7
6
4
3
2
2
2
2
1
1
1
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产品编号 ABIN5556680
3,929.33 ¥
(含税, 含运费)
来自4A Biotech Co.,Ltd.(本地经销商)
获取报价
中国 北京 101111
No. 88 KeChuang 6th Street
Room 801-803
Beijing Economic Technological Development Area
4A Biotech Co.,Ltd.
Tel 400-7060-959
传真 +86 10 56315212-8813
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1490889 IP WB Biotin Mouse IgG1 AA 1234-1259 Log in to see 2B5
1 ABIN1867784 ICC IHC IP WB Rabbit IgG AA 707-964 Log in to see Polyclonal
1 ABIN213195 IP WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN385582 IP WB Mouse IgG1 AA 1234-1259 Log in to see 2B5
1 ABIN385583 IP WB Mouse IgG1 AA 1234-1259 Log in to see 2B5
1 ABIN385598 IP WB Mouse IgG1 AA 1234-1259 Log in to see 2C3
1 ABIN385599 IP WB Mouse IgG1 AA 1234-1259 Log in to see 2C3
1 ABIN385588 IP WB Mouse IgG1 AA 1234-1259 Log in to see 2B5
1 ABIN385601 IP WB Mouse IgG1 AA 1234-1259 Log in to see 2C3
1 ABIN385251 IP WB Mouse IgG2a, kappa Log in to see 2F12
1 ABIN385252 IP WB Mouse IgG2a, kappa Log in to see 2F12
1 ABIN232947 IP WB Mouse IgG1 Log in to see
1 ABIN205790 IP WB Mouse IgG2a, kappa Log in to see
1 ABIN230900 IP WB Mouse IgG2a, kappa Log in to see
1 ABIN385556 FACS IF IP Mouse IgG1 Extracellular Domain Log in to see H3-105-5
1 ABIN385554 FACS IF IP Mouse IgG1 Extracellular Domain Log in to see H3-105-5
1 ABIN385254 IP WB Mouse IgG2a, kappa Log in to see 2F12
1 ABIN1901712 IP WB Rabbit AA 1292-1342 Log in to see Polyclonal
1 ABIN385557 Inhibition FACS IF IP Mouse IgG1 Extracellular Domain Log in to see H3-105-5 or AB105
1 ABIN1901710 IP Rabbit AA 1275-1325 Log in to see Polyclonal

General

抗原 V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) 抗体
抗原表位 AA 1283-1323, C-Term
(41), (40), (27), (22), (21), (19), (15), (15), (15), (15), (15), (14), (13), (12), (10), (10), (10), (9), (8), (7), (7), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 人, 小鼠, 大鼠
(517), (197), (172), (14), (7), (6), (6), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1)
宿主
(302), (213), (27), (3)
克隆类型
多克隆
标记 This ERBB3 antibody is un-conjugated
(14), (11), (11), (11), (10), (10), (7), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2)
应用范围 Immunoprecipitation (IP), Western Blotting (WB)
(311), (194), (148), (109), (107), (84), (67), (56), (10), (8), (8), (8), (7), (6), (4), (3), (2), (2), (2), (2), (1), (1), (1)
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ERBB3抗体详情

ERBB3目标详情 使用细节 贮存及处理 图像
特异性 The antibody is directed against Human HER3. It can detect HER3 from Human, Mouse and Rat sources. Reactivity of this antibody with HER3 from other species is unknown.
产品特性 Concentration: 5.74 mg/mL (by UV absorbance at 280 nm)
纯化方法 Protein A Chromatography followed by cross adsorption against GST and extensive dialysis against the buffer stated below.Assay by immunoelectro-phoresis resulted in a single precipitin arc against anti-Rabbit.
免疫原 This whole serum was prepared by repeated immunizations with a GST-HER3 fusion protein corresponding to amino acids 1283 to 1323 (40 amino acids) at the carboxy-terminus of human HER3.

ERBB3目标详情

ERBB3抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 ERBB3 / HER3 (ERBB3 Antibody 摘要)
背景 The human Epidermal Growth Factor Receptor (EGFR) family is a family of receptor tyrosine kinases consisting of 4 members: EGFR, HER2, HER3 and HER4. These receptors are expressed on a wide variety of tissue types and have been implicated in many human cancers, including breast, gastric, colon and prostate. Strong expression of both HER3 and HER2 (also known as p185neu) by tumor cells can be associated with poor outcome for patients. The ligand for HER3 and HER4 is called Neu Differentiation Factor (NDF) or Heregulin. In some instances, antibodies against these receptors prove effective in combination therapy regimens for treatment of the disease. Signaling through the EGFR family involves the combinatorial dimerization of the four known family members and is mediated by at least 8 different hormones, including EGF and the heregulins. Heregulin binding and tyrosine phosphorylation by HER3 or HER4 is enhanced in the presence of HER2. Structurally the members of the EGFR family are 1210 to 1342 amino acids in length with approximately 650 amino acids of the extracellular domain being heavily glycosylated. The extracellular domains show up to 70 % sequence homology.Synonyms: ERBB-3, HER-3, Proto-oncogene-like protein c-ErbB-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, c-erbB-3
基因ID 2065
NCBI登录号 NP_001005915
UniProt P21860
途径 RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

使用细节

ERBB3抗体详情 ERBB3目标详情 贮存及处理 图像 回页首
应用备注 Anti-HER3 antibody is specifically designed for Immunoprecipitation and can be used forImmunoblotting in conjunction with a detection antibody like anti-phosphotyrosine. Reactivity in other assays is likely, but has not been determined. Recognition of HER3 isindependent of the phosphorylation status of the molecule. Human prostate cell lines(LNCap) or human breast cell line (MDA-453) are typically used as positive control sources. Recommended Dilutions: Immunoprecipitation: Use approximately 5 μL of the antibody. The Immunoprecipitation
限制 仅限研究用

贮存及处理

ERBB3抗体详情 ERBB3目标详情 使用细节 图像 回页首
浓度 5.74 mg/mL
缓冲液 0.02 M potassium phosphate, 0.12 M sodium chloride, pH 7.2 with 0.01 % Sodium Azide as preservative without Stabilizers.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Dilute only prior to immediate use. Avoid cycles of freezing and thawing.
储存条件 -20 °C
储存方法 Store vial at -20 °C or below prior to opening. Aliquot contents and freeze at -20 °C or below.