anti-SRSF1 (SRSF1) 抗体产品概述

Full name:
anti-serine/arginine-Rich Splicing Factor 1 抗体 (SRSF1)
在www.antibodies-online.cn可供66 serine/arginine-Rich Splicing Factor 1 (SRSF1) 抗体的17不同的供货商。 再加上,我们可以发SRSF1 蛋白 (14)SRSF1 试剂盒 (11)和数多这个蛋白质的别的产品。 总共99 SRSF1产品已列进来了。
别名:
1110054N12Rik, 5730507C05Rik, 6330415C05Rik, AI482334, Asf, Asf1, AW491331, CG9383, dASF/SF2, dAsf1, DKFZp469K2419, Dmel\\CG9383, l(3)76BDq, Sf2, SF2p33, Sfrs1, sfrs1b, SRp30a, wu:fb80g05, zgc:65898, zgc:76897, zgc:111894
列出全部抗体 基因 基因ID UniProt
SRSF1 6426 Q07955
SRSF1 110809 Q6PDM2
SRSF1 689890  

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引用最多的anti-SRSF1 抗体

  1. Cow (Bovine) Polyclonal SRSF1 Primary Antibody for IHC, WB - ABIN2779013 : Velazquez-Dones, Hagopian, Ma, Zhong, Zhou, Ghosh, Fu, Adams: Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for 2779013

  2. Human Polyclonal SRSF1 Primary Antibody for ICC, IF - ABIN4353084 : Brown, Dobrikov, Gromeier et al.: Mitogen-activated protein kinase-interacting kinase regulates mTOR/AKT signaling and controls the serine/arginine-rich protein kinase-responsive type 1 internal ribosome entry site-mediated ... in Journal of virology 2014 (PubMed)
    Show all 2 references for 4353084

  3. Human Polyclonal SRSF1 Primary Antibody for EIA, IHC (p) - ABIN453373 : Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications. in Molecular & cellular proteomics : MCP 2007 (PubMed)

更多抗SRSF1的相互作用对抗体

Fruit Fly (Drosophila melanogaster) serine/arginine-Rich Splicing Factor 1 (SRSF1) interaction partners

  1. DLP (显示 DMD 抗体) and ASF1 are part of a predeposition complex, which is recruited by XNP (显示 ATRX 抗体) and is necessary to prevent DNA exposure in the nucleus.

  2. ASF1 cellular levels are tightly controlled by distinct pathways and provide a molecular mechanism for post-translational regulation of dASF1 and hASF1a (显示 ASF1A 抗体) by TLK (显示 TLK2 抗体) kinases.

  3. dASF1 has a direct role in modifying chromatin structure during DNA replication and this function of dASF1 is important for the processivity of the replication machinery.

  4. Asf1 is directed via interactions with sequence-specific complexes to mediate silencing of specific target genes.

  5. Histone chaperones ASF1 and NAP1 (显示 NAP1L1 抗体) differentially modulate removal of active histone marks by LID-RPD3 (显示 HDAC1 抗体) complexes during NOTCH (显示 NOTCH1 抗体) silencing.

Human serine/arginine-Rich Splicing Factor 1 (SRSF1) interaction partners

  1. high level of SF2, as a novel oncoprotein in RCC (显示 XRCC1 抗体), was significantly associated with poor survival in a large cohort of RCC (显示 XRCC1 抗体) specimens. Taken together, our study presents a road map for the prediction and validation of miR (显示 MLXIP 抗体)-766-3p/SF2 axis and thus imparts a therapeutic way for further RCC (显示 XRCC1 抗体) progression.

  2. The authors found that RNA recognition motif 1 (RRM1 (显示 RRM1 抗体)) in SRSF1 binds PP1 (显示 PPA1 抗体) and represses its catalytic function through an allosteric mechanism.

  3. We present a joint atomistic molecular dynamics (MD) and experimental study of two RRM-containing proteins bound with their single-stranded target RNAs, namely the Fox-1 (显示 A2BP1 抗体) and SRSF1 complexes.The simulations predict unanticipated specific participation of Arg142 at the protein-RNA interface of the SRFS1 complex, which is subsequently confirmed by NMR and ITC measurements

  4. Using NMR spectroscopy with two separately expressed domains of SRSF1, we showed that several residues in the RNA-binding motif 2 interact with the N-terminal region of the RS domain (RS1 (显示 RS1 抗体)).

  5. Especially, in SRSF1 morphants, bone cartilage formation was reduced in the brain and Nkx-2.5 (显示 NKX2-5 抗体) expression was dramatically reduced in the heart of SRSF1 morphants. In addition, a dramatic reduction in functional chordin (显示 CHRD 抗体) RNA in SRSF1 morphants was observed suggesting that chordin (显示 CHRD 抗体) is one of the targets of SRSF1. Thus, we concluded that SRSF1 is an essential factor for pattern formation including heart, cartilage and germ lay

  6. results strongly support SRSF1 as a prognostic biomarker in SCLC and provide a rationale for personalized therapy in SCLC

  7. NSrp70 (显示 NSRP1 抗体) acts as a new molecular counterpart for alternative splicing of target RNA, counteracting SRSF1 and SRSF2 (显示 SRSF2 抗体) splicing activity.

  8. we have identified for the first time a potential mechanism that involves the essential splicing factor (显示 SLU7 抗体) ASF/SF2 through which morphine regulates splicing specificity of the MOR (显示 OPRM1 抗体) encoding gene, OPRM1 (显示 OPRM1 抗体).

  9. Global splicing analysis with RNA-seq revealed that exons carrying the hnRNP H (显示 HNRNPH1 抗体)-binding GGGGG motif are predisposed to be skipped compared to those carrying the SRSF1-binding GGAGG motif in both human and mouse brains.

  10. We present experimental evidence that splicing factor (显示 SLU7 抗体) SRSF1, SRSF2 (显示 SRSF2 抗体), U2AF35 (显示 U2AF1 抗体), U2AF65 (显示 U2AF59 抗体) and KHSRP (显示 KHSRP 抗体) expression levels in gastrointestinal tract (colon, gastric and pancreatic) tumors differ compare to healthy tissues and in cell lines

Mouse (Murine) serine/arginine-Rich Splicing Factor 1 (SRSF1) interaction partners

  1. The expression levels of three splicing factors, ESRP1 (显示 ESRP1 抗体), PTB (显示 PTBP1 抗体) and SF2/ASF, are significantly altered during cardiac hypertrophy in mice.

  2. RRP1B suppresses metastatic progression by altering the transcriptome through its interaction with splicing regulators such as SRSF1

  3. Deletion of RRM1 (显示 RRM1 抗体) eliminated the splicing activity of SRSF1 and thus cellular transformation.

  4. Specific effects on regulated splicing by SR proteins SRSF1 and SRSF2 (显示 SRSF2 抗体) depends on a complex set of relationships with multiple other SR proteins in mammalian genomes.

  5. Treatment with IL-17 (显示 IL17A 抗体) prolongs the half-life of chemokine (显示 CCL1 抗体) CXCL1 (显示 CXCL1 抗体) mRNA via the adaptor TRAF5 (显示 TRAF5 抗体) and the splicing-regulatory factor SF2 (ASF).

  6. analysis of the miRNA-mediated interaction between leukemia/lymphoma-related factor (LRF (显示 ZBTB7A 抗体)) and alternative splicing factor/splicing factor (显示 SLU7 抗体) 2 (ASF/SF2) affects cell senescence and apoptosis

  7. Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 (显示 SMN1 抗体) causes spinal muscular atrophy in the absence of SMN1 (显示 SMN1 抗体)

  8. Both hnRNP A1 (显示 HNRNPA1 抗体) and alternative splicing factor/splicing factor (显示 SLU7 抗体) 2 contents rose in adenomas and during injury-induced hyperplasia compared to control lungs

  9. These results highlight the requirement of Sfrs1-mediated alternative splicing for the survival of retinal neurons, with sensitivity defined by the window of time in which the neuron was generated.

SRSF1 抗原简介

Antigen Summary

This gene encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 13.

Alternative names and synonyms associated with SRSF1

  • anti-silencing factor 1 (asf1) 抗体
  • serine/arginine-rich splicing factor 1 (srsf1) 抗体
  • serine/arginine-rich splicing factor 1 (SRSF1) 抗体
  • serine/arginine-rich splicing factor 1 (Srsf1) 抗体
  • serine/arginine-rich splicing factor 1b (srsf1b) 抗体
  • 1110054N12Rik 抗体
  • 5730507C05Rik 抗体
  • 6330415C05Rik 抗体
  • AI482334 抗体
  • Asf 抗体
  • Asf1 抗体
  • AW491331 抗体
  • CG9383 抗体
  • dASF/SF2 抗体
  • dAsf1 抗体
  • DKFZp469K2419 抗体
  • Dmel\\CG9383 抗体
  • l(3)76BDq 抗体
  • Sf2 抗体
  • SF2p33 抗体
  • Sfrs1 抗体
  • sfrs1b 抗体
  • SRp30a 抗体
  • wu:fb80g05 抗体
  • zgc:65898 抗体
  • zgc:76897 抗体
  • zgc:111894 抗体

Protein level used designations for SRSF1

CG9383-PA , CG9383-PB , anti- silencing function 1 , anti-silencing factor , asf1-PA , asf1-PB , splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor) , ASF-1 , SR splicing factor 1 , alternative-splicing factor 1 , pre-mRNA-splicing factor SF2, P33 subunit , splicing factor 2 , splicing factor, arginine/serine-rich 1 , splicing factor arginine/serine-rich 1 , splicing factor, arginine/serine-rich 1B , ASF/SF2 , pre-mRNA-splicing factor SRp30a , splicing factor, arginine/serine-rich 1 (ASF/SF2) , serine/arginine-rich splicing factor 1B , splicing factor, arginine/serine-rich 1b

GENE ID SPECIES
40141 Drosophila melanogaster
399226 Xenopus laevis
772264 Gallus gallus
6426 Homo sapiens
609693 Canis lupus familiaris
654327 Sus scrofa
615796 Bos taurus
110809 Mus musculus
689890 Rattus norvegicus
100173318 Pongo abelii
393565 Danio rerio
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