M-CSF/CSF1 蛋白
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- 抗原 See all M-CSF/CSF1 (CSF1) 蛋白
- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 序列
- MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP
- 产品特性
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Purified recombinant Human M-CSF protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of M-NFS-60 cells is 1 x 10^6 units/mg. - 纯度
- > 98 % pure
- 内毒素水平
- < 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product CSF1 蛋白
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Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) protein
CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) protein (His-Avi Tag)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (His tag)CSF1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) protein (His-Avi Tag,Biotin)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190), (Isoform 3) (Active) proteinCSF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as analyzed by non-reducing SDS-PAGE. Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (Active) proteinCSF1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (Active) proteinCSF1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-187) (Active) proteinCSF1 宿主: 小鼠 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) (Active) protein (His tag)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) (Active) protein (His tag,AVI tag,Biotin)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 说明
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Biological activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of M-NFS-60 cells is 1 x 10^6 units/mg.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
- 缓冲液
- Lyophilized from 5 mM tris, pH 8.0 with 105 mM NaCl.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- RT/-20 °C
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- 抗原
- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
- 别名
- M-CSF (CSF1 产品)
- 别名
- CSF-1 Protein, MCSF Protein, C87615 Protein, Csfm Protein, op Protein, csf1-1 Protein, zgc:172186 Protein, CSF1 Protein, csf1-2 Protein, zgc:158436 Protein, colony stimulating factor 1 Protein, colony stimulating factor 1 (macrophage) Protein, colony stimulating factor 1a (macrophage) Protein, macrophage colony-stimulating factor 1 Protein, macrophage colony stimulating factor Protein, colony stimulating factor 1b (macrophage) Protein, CSF1 Protein, Csf1 Protein, csf1a Protein, LOC396599 Protein, LOC100860895 Protein, csf1b Protein
- 背景
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M-CSF is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. The human is reactive in Mouse systems, but the Mouse molecule exhibits no activity on human cells.
Alternative Names: MGI-IM protein, Macrophage Colony Stimulating Factor protein, CSF-1 protein - 分子量
- 36.4 kDa
- 途径
- RTK signaling
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