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Interferon gamma Protein (IFNG)

IFNG 宿主: 人 宿主: HEK-293 Cells Recombinant >93 % as determined by SDS-PAGE. WB Active
产品编号 ABIN2566722
发货至: 中国
  • 抗原 See all Interferon gamma (IFNG) 蛋白
    Interferon gamma (IFNG)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
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    资源
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    HEK-293 Cells
    应用范围
    Western Blotting (WB)
    产品特性

    Determined by a cytotoxicity assay using HT-29 cells. The ED50 < 0. 05 ng/mL, corresponding to a specific activity of >2X107 Unit/mg.

    纯度
    >93 % as determined by SDS-PAGE.
    Top Product
    Discover our top product IFNG 蛋白
  • 应用备注
    This recombinant protein can be used for WB. For research use only.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -80 °C,-20 °C
    储存方法
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • 抗原
    Interferon gamma (IFNG)
    别名
    Interferon gamma (IFNG 产品)
    别名
    IFG Protein, IFI Protein, IFN-g Protein, Ifg Protein, IFNG2 Protein, IFN-gamma Protein, IFN-G Protein, IFNG Protein, IFNgamma Protein, TCRalpha Protein, INF-G Protein, ifng Protein, interferon gamma Protein, interferon, gamma 1-2 Protein, IFNG Protein, Ifng Protein, ifng1-2 Protein
    背景
    Interferon-gamma (IFN-γ/IFNG) is a dimerized soluble cytokine that is the only member of the type II class of interferon. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-γ belongs. IFN-gamma has been used in a wide variety of clinical indications. Interferon-gamma (IFNgamma) is a central regulator of the immune response and signals via the Janus Activated Kinase (JAK)-Signal Transducer and Activator of Transcription (STAT) pathway. Interferon gamma has broader roles in activation of innate and adaptive immune responses to viruses and tumors, in part through upregulating transcription of genes involved in cell cycle regulation, apoptosis, and antigen processing/presentation. Despite this, rodent and human trophoblast cells show dampened responses to IFNG that reflect the resistance of these cells to IFNG-mediated activation of major histocompatibility complex (MHC) class II transplantation antigen expression.
    分子量
    16.8 kDa
    基因ID
    3458
    UniProt
    P01579
    途径
    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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