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Interferon gamma Protein (IFNG) (AA 23-155)

IFNG 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as analyzed by reducing SDS-PAGE. Active
产品编号 ABIN2018007
发货至: 中国
  • 抗原 See all Interferon gamma (IFNG) 蛋白
    Interferon gamma (IFNG)
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 23-155
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    小鼠
    资源
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    大肠杆菌(E. Coli)
    产品特性
    ED50<0.15 ng/mL, measured by cytotoxicity assay using WEHI-279 cells.
    AA 23-155, expressed with an N-terminal Met.
    纯度
    > 95 % as analyzed by reducing SDS-PAGE.
    内毒素水平
    < 1 EU/μg, determined by LAL method.
    Top Product
    Discover our top product IFNG 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant mouse IFN gamma (rmIFN-γ) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmIFN-γ should be stable up to 1week at 4°C or up to 2 months at -20°C.
    有效期
    6 months
  • 抗原
    Interferon gamma (IFNG)
    别名
    Interferon-gamma (IFN-Gamma) (IFNG 产品)
    别名
    IFG Protein, IFI Protein, IFN-g Protein, Ifg Protein, IFNG2 Protein, IFN-gamma Protein, IFN-G Protein, IFNG Protein, IFNgamma Protein, TCRalpha Protein, INF-G Protein, ifng Protein, interferon gamma Protein, interferon, gamma 1-2 Protein, IFNG Protein, Ifng Protein, ifng1-2 Protein
    背景
    Sharing 41 % sequence identity with human Interferon gamma (hIFN--γ), mouse IFN gamma (mIFN--γ) is a macrophage-activating factor.The active form of IFN--γ is an antiparallel dimer that sets off IFN--γ/JAK/STAT pathway. IFN--γ signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity.While IFN--γ-induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN--γ is also implicated in resistance to NK cell and CTL responses and in immune escape in avariety of cancers. Recombinant mouse IFN gamma (rmIFN-γ) produced in E. coli is a non-glycosylated polypeptide chain of 134 amino acids. A fully biologically active molecule, rmIFN--γ has a molecular mass of 15 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary refolding and chromatographic techniques.
    Synonyms: Type II interferon, T cell interferon, MAF, IFNG, IFG, IFI
    分子量
    15 kDa, observed by reducing SDS-PAGE.
    UniProt
    P01580
    途径
    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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