anti-NADPH Oxidase 4 (NOX4) 抗体产品概述

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anti-NADPH Oxidase 4 抗体 (NOX4)
在www.antibodies-online.cn可供182 NADPH Oxidase 4 (NOX4) 抗体的20不同的供货商。 再加上,我们可以发NADPH Oxidase 4 试剂盒 (24)NADPH Oxidase 4 蛋白 (13)和数多这个蛋白质的别的产品。 总共226 NADPH Oxidase 4产品已列进来了。
AI648021, KOX, KOX-1, NOX4, RENOX

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引用最多的anti-NADPH Oxidase 4 抗体

  1. Cow (Bovine) Polyclonal NOX4 Primary Antibody for ICC, IHC (fro) - ABIN189715 : Maranchie, Zhan: Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma. in Cancer research 2005 (PubMed)
    Show all 48 references for 189715

  2. Human Polyclonal NOX4 Primary Antibody for IHC (p), WB - ABIN657946 : Manea, Tanase, Raicu, Simionescu: Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-kappaB in human aortic smooth muscle cells. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 3 references for 657946

  3. Human Polyclonal NOX4 Primary Antibody for FACS, ICC - ABIN258606 : Basuroy, Bhattacharya, Leffler, Parfenova: Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cells. in American journal of physiology. Cell physiology 2009 (PubMed)
    Show all 2 references for 258606

  4. Mouse (Murine) Polyclonal NOX4 Primary Antibody for IHC, WB - ABIN3023201 : Wingler, Wünsch, Kreutz, Rothermund, Paul, Schmidt: Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo. in Free radical biology & medicine 2001 (PubMed)

  5. Human Polyclonal NOX4 Primary Antibody for IHC, IHC (p) - ABIN409683 : Zhang, Liu, Hu: Inhibiting cancer metastasis via targeting NAPDH oxidase 4. in Biochemical pharmacology 2013 (PubMed)

  6. Dog (Canine) Polyclonal NOX4 Primary Antibody for IF (p), IHC (p) - ABIN737526 : Khan, Byer, Khan: Exposure of Madin-Darby canine kidney (MDCK) cells to oxalate and calcium oxalate crystals activates nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase. in Urology 2014 (PubMed)

  7. Human Polyclonal NOX4 Primary Antibody for IF (p), IHC (p) - ABIN702610 : Kashiwabara, Ambe, Nakagawa, Watanabe: Immunohistochemical localization of Nox in mouse circumvallate papillae. in Tissue & cell 2015 (PubMed)

更多抗NADPH Oxidase 4的相互作用对抗体

Human NADPH Oxidase 4 (NOX4) interaction partners

  1. data suggest that monocytic Nox4 is a central regulator of actin dynamics, and induction of Nox4 is the rate-limiting step in metabolic stress-induced monocyte priming and dysfunction associated with accelerated atherosclerosis and the progression of atherosclerotic plaques

  2. findings demonstrate that manipulation of the host PI3K (显示 PIK3CA 抗体)/Akt (显示 AKT1 抗体) signaling pathway and Nox4 gene expression is a novel mechanism involved in T. gondii survival and proliferation

  3. Loss of NOX4 increases actomyosin levels and favours an epithelial to amoeboid transition contributing to tumour aggressiveness.

  4. NOX2 (显示 CYBB 抗体), NOX4, and mitochondrial-derived reactive oxygen species contribute to angiopoietin-1 (显示 ANGPT1 抗体) signaling and angiogenic responses in endothelial cells.

  5. Mechanistically, HO-1 (显示 HMOX1 抗体) induction by all CRLPs requires NADPH oxidase 4, with PUFA-containing particles additionally dependent upon mitochondrial reactive oxygen species.These studies define new molecular pathways coupling endothelial cell activation by model CMRs with adaptive regulation of Nrf2 (显示 GABPA 抗体)-dependent HO-1 (显示 HMOX1 抗体) expression

  6. NOX4 knockout cell lines showed reduced cell proliferation with an increase of sub-G1 cell population and the decrease of S/G2 (显示 STRN3 抗体)/M population, and resulted in a dramatic decrease in invadopodium formation and the invasive activity. NOX4 deficiency caused a decrease in focal adhesions and cell migration in HeLa cells. The results suggest that NOX4 is required for both efficient proliferation and invasion of HeLa cells.

  7. Thioredoxin (显示 TXN 抗体) attenuates oxidized low-density lipoprotein induced oxidative stress in human umbilical vein endothelial cells by reducing NOX2 (显示 CYBB 抗体)-NOX4 activity.

  8. Nox4-derived H2O2 in part activates Nox2 (显示 CYBB 抗体) to increase mitochondrial ROS (显示 ROS1 抗体) via pSer36-p66Shc (显示 SHC1 抗体), thereby enhancing VEGFR2 (显示 KDR 抗体) signaling and angiogenesis in endothelial cells.

  9. TGF-beta1 (显示 TGFB1 抗体) increases NADPH oxidase 4 (NOX4) mRNA and protein expression in normal human lung fibroblasts (NHLFs) and causes nuclear export of HDAC4 (显示 HDAC4 抗体).

  10. Nox4 should contribute to the pathological processes insubarachnoid hemorrhage(SAH (显示 ACSM3 抗体))-induced early brain injury (EBI (显示 TBL1X 抗体)), and there was not an overlay effect of Nox2 (显示 CYBB 抗体) inhibition and Nox4 inhibition on preventing SAH (显示 ACSM3 抗体)-induced EBI (显示 TBL1X 抗体).

Cow (Bovine) NADPH Oxidase 4 (NOX4) interaction partners

  1. Peroxide derived from superoxide generated by Nox4 appears to maintain a basal relaxation in bovine pulmonary arteries under normoxic conditions, which is removed under hypoxia leading to hypoxic pulmonary vasoconstriction.

Rabbit NADPH Oxidase 4 (NOX4) interaction partners

  1. proteasome inhibition completely prevented endoplasmic reticulum stress-induced increase in NADPH oxidase (显示 NOX1 抗体) activity, as well as increases in Nox4 isoform and protein disulfide isomerase (显示 P4HB 抗体) mRNA expression

Mouse (Murine) NADPH Oxidase 4 (NOX4) interaction partners

  1. Nox2 (显示 CYBB 抗体)- and Nox4-derived reactive oxygen species contribute to stem cell pluripotency maintenance and self-renewal.

  2. FYN (显示 FYN 抗体) is activated by oxidative stress and serves as a negative feedback regulator of NOX4 in cardiomyocytes during cardiac remodeling

  3. NOX4-derived reactive oxygen species in general, and possibly superoxide in particular, are involved in flow-stimulated inner medullary collecting duct ET-1 (显示 EDN1 抗体) production.

  4. CYLD (显示 CYLD 抗体) contributes to the transdifferentiation of adventitial fibroblasts via deubiquitinating Nox4 and may play a role in vascular remodeling.

  5. Data suggests that ROS (显示 ROS1 抗体) produced during primitive endoderm differentiation is dependent in part on increased NOX1 (显示 NOX1 抗体) and NOX4 levels, which is under the control of GATA6 (显示 GATA6 抗体). Furthermore, these results suggest that the combined activity of multiple NOX proteins is necessary for the differentiation of F9 cells to primitive endoderm.

  6. Nox4 is upregulated in pericytes in peri (显示 POSTN 抗体)-infarct areas after acute brain ischemia and may enhance blood-brain barrier breakdown through activation of NFkappaB and matrix metalloproteinase 9 (显示 MMP9 抗体), thereby causing enlargement of infarct volume.

  7. Deficiency of NOX4 resulted in reduced expression of carnitine palmitoyltransferase 1A (CPT1A (显示 CPT1A 抗体)), which is a key mitochondrial enzyme in the fatty acid oxidation (FAO) pathway. The reduced FAO resulted in less activation of the nucleotide-binding domain, leucine-rich-repeat-containing receptor (NLR (显示 CXCR5 抗体)), pyrin-domain-containing 3 (NLRP3 (显示 NLRP3 抗体)) inflammasome in macrophages.

  8. NOX4- and NOX1 (显示 NOX1 抗体)-derived ROS (显示 ROS1 抗体) contribute to atherosclerosis in the aortic sinus of diabetic ApoE (显示 APOE 抗体) knockout mice.

  9. CD44V6 is part of a positive-feedback loop with TGFbeta1 (显示 TGFB1 抗体)/TGFbetaRI signaling that acts to increase NOX4/ROS (显示 ROS1 抗体) production, which is required for myofibroblast differentiation, myofibroblast differentiation, myofibroblast extracellular matrix production, myofibroblast invasion, and myofibroblast contractility.

  10. Nox4 mitigates cerebral artery structural changes in a murine model of Marfan syndrome.

Pig (Porcine) NADPH Oxidase 4 (NOX4) interaction partners

  1. MRTF down-regulation/inhibition suppresses TGFbeta (显示 TGFB1 抗体)/contact disruption-provoked Nox4 protein and mRNA expression, Nox4 promoter activation, and reactive oxygen species production.

  2. Nox4 NADPH oxidase (显示 NOX1 抗体) mediates oxidative stress and apoptosis caused by TNF-alpha (显示 TNF 抗体) in cerebral vascular endothelial cells.

  3. Nox4 NADPH oxidase (显示 NOX1 抗体)-derived reactive oxygen species also initiate a cell survival mechanism by increasing production of carbon monoxide by constitutive heme oxygenase-2 (显示 HMOX2 抗体).

NADPH Oxidase 4 (NOX4) 抗原简介

Antigen Summary

This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with NADPH Oxidase 4 (NOX4)

  • NADPH oxidase 4 (NOX4) 抗体
  • NADPH oxidase 4 (nox4) 抗体
  • NADPH oxidase 4 (PTRG_09562) 抗体
  • NADPH oxidase 4 (Nox4) 抗体
  • AI648021 抗体
  • KOX 抗体
  • KOX-1 抗体
  • NOX4 抗体
  • RENOX 抗体

Protein level used designations for anti-NADPH Oxidase 4 (NOX4) 抗体

NADPH oxidase 4 , predicted NADPH oxidase-4 , kidney oxidase-1 , kidney superoxide-producing NADPH oxidase , renal NAD(P)H-oxidase , KOX-1 , superoxide-generating NADPH oxidase 4 , kox-1

419012 Gallus gallus
619226 Ciona intestinalis
705931 Macaca mulatta
735636 Pan troglodytes
6347852 Pyrenophora tritici-repentis Pt-1C-BFP
50507 Homo sapiens
378474 Bos taurus
100034665 Ovis aries
100339697 Oryctolagus cuniculus
50490 Mus musculus
85431 Rattus norvegicus
100523323 Sus scrofa
485144 Canis lupus familiaris
100171782 Pongo abelii
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