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NAE1 抗体

(NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
NAE1 抗体  (AA 1-534) NAE1 抗体  (AA 1-534) NAE1 抗体 (AA 1-534) (ABIN563865)

NAE1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4E8-H3 unconjugated

NAE1 抗体  (C-Term) NAE1 抗体  (C-Term) NAE1 抗体 (C-Term) (ABIN359509)

NAE1 适用: 人 EIA, IHC (p), WB 宿主: 兔 Polyclonal unconjugated

NAE1 抗体  (Regulatory Subunit) NAE1 抗体  (Regulatory Subunit) NAE1 抗体 (Regulatory Subunit) (ABIN7161137)

NAE1 适用: 人 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated

NAE1 抗体 by 适用

Find NAE1 抗体 for a variety of species such as anti-Human NAE1, anti-Mouse NAE1, anti-Rat NAE1. The species listed below are among those available. Click on a link to go to the corresponding products.

NAE1 抗体 by 应用范围

Find NAE1 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

NAE1 抗体 by 抗体来源

Find NAE1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

NAE1 抗体 by 抗原表位

Find NAE1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

NAE1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal NAE1 抗体. Click on a link to go to the corresponding products.

NAE1 抗体 by 克隆

Find NAE1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

NAE1 抗体 by 标记

Find NAE1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular NAE1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application EIA, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN359509
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7161137
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
  • (1)
Cat. No. ABIN563864
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application IP, WB
Validations
  • (2)
Cat. No. ABIN948746
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application EIA, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN950470
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7240514
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6750418
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN7260999
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN3043281
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
Cat. No. ABIN2788045
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
Cat. No. ABIN6389000
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
Cat. No. ABIN1714592
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
Cat. No. ABIN7094068
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IP, WB
Validations
Cat. No. ABIN7116769
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
Cat. No. ABIN656991
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our NAE1 抗体

Park, Ju, Park, Song, Shin, Lee, Jeong, Yu, Lee, Cho, Kim, Kim, Kim, Park, Chun: "PPARγ neddylation essential for adipogenesis is a potential target for treating obesity." in: Cell death and differentiation, Vol. 23, Issue 8, pp. 1296-311, (2016) (PubMed).

Konforti: "More than the sum of its parts." in: Cell reports, Vol. 1, Issue 1, pp. 1, (2012) (PubMed).

Toth, Yang, Dahl, Petroski: "A gatekeeper residue for NEDD8-activating enzyme inhibition by MLN4924." in: Cell reports, Vol. 1, Issue 4, pp. 309-16, (2012) (PubMed).

Walden, Podgorski, Schulman: "Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8." in: Nature, Vol. 422, Issue 6929, pp. 330-4, (2003) (PubMed).

Chen, Liu, Naumovski, Neve: "ASPP2 inhibits APP-BP1-mediated NEDD8 conjugation to cullin-1 and decreases APP-BP1-induced cell proliferation and neuronal apoptosis." in: Journal of neurochemistry, Vol. 85, Issue 3, pp. 801-9, (2003) (PubMed).

Chen, Liu, McPhie, Hassinger, Neve: "APP-BP1 mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimer's disease brain." in: The Journal of cell biology, Vol. 163, Issue 1, pp. 27-33, (2003) (PubMed).

Chen, McPhie, Hirschberg, Neve: "The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons." in: The Journal of biological chemistry, Vol. 275, Issue 12, pp. 8929-35, (2000) (PubMed).

Hori, Osaka, Chiba, Miyamoto, Okabayashi, Shimbara, Kato, Tanaka: "Covalent modification of all members of human cullin family proteins by NEDD8." in: Oncogene, Vol. 18, Issue 48, pp. 6829-34, (2000) (PubMed).

Chow, Korenberg, Chen, Neve: "APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein." in: The Journal of biological chemistry, Vol. 271, Issue 19, pp. 11339-46, (1996) (PubMed).

Aliases for NAE1 抗体

beta-Amyloid precursor protein binding protein 1 (APP-BP1) 抗体
NEDD8 activating enzyme E1 subunit 1 (NAE1) 抗体
NEDD8 activating enzyme E1 subunit 1 (Nae1) 抗体
NEDD8 activating enzyme E1 subunit 1 S homeolog (nae1.S) 抗体
nedd8 activating enzyme E1 subunit 1 (nae1) 抗体
NEDD8-activating enzyme E1 regulatory subunit (ula-1) 抗体
59kDa 抗体
A-116A10.1 抗体
anon-WO0140519.225 抗体
APPBP1 抗体
Appbp1 抗体
appbp1 抗体
CG7828 抗体
dAPP-BP1 抗体
dAPPBP1 抗体
Dmel\\CG7828 抗体
ula-1 抗体
zgc:66148 抗体
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