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CHEK2 抗体

CHEK2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN965891
发货至: 中国
  • 抗原 See all CHEK2 抗体
    CHEK2 (Checkpoint Kinase 2 (CHEK2))
    适用
    • 261
    • 96
    • 82
    • 16
    • 14
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 242
    • 20
    • 1
    • 1
    克隆类型
    • 228
    • 36
    多克隆
    标记
    • 116
    • 14
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    • 12
    • 12
    • 12
    • 12
    • 12
    • 10
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    • 7
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    • 2
    • 2
    • 2
    • 1
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    This CHEK2 antibody is un-conjugated
    应用范围
    • 206
    • 80
    • 79
    • 72
    • 37
    • 36
    • 33
    • 28
    • 28
    • 19
    • 18
    • 5
    • 1
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    Immunohistochemistry (IHC)
    特异性
    Chk2 (Ab-68) antibody detects endogenous levels of total Chk2 protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    The antiserum was produced against synthesized non-phosphopeptide derived from human Chk2 around the phosphorylation site of threonine 68.
    Top Product
    Discover our top product CHEK2 Primary Antibody
  • 应用备注
    WB: 1:500~1:1000
    IHC: 1:50~1:100.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100ug/100ul.
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Bhoumik, Takahashi, Breitweiser, Shiloh, Jones, Ronai: "ATM-dependent phosphorylation of ATF2 is required for the DNA damage response." in: Molecular cell, Vol. 18, Issue 5, pp. 577-87, (2005) (PubMed).

    Gorgoulis, Vassiliou, Karakaidos, Zacharatos, Kotsinas, Liloglou, Venere, Ditullio, Kastrinakis, Levy, Kletsas, Yoneta, Herlyn, Kittas, Halazonetis: "Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions." in: Nature, Vol. 434, Issue 7035, pp. 907-13, (2005) (PubMed).

    Jin, Kurosu, Yamaguchi, Arai, Miura: "Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis." in: Oncogene, Vol. 24, Issue 12, pp. 1973-81, (2005) (PubMed).

    Li, Stern: "Regulation of CHK2 by DNA-dependent protein kinase." in: The Journal of biological chemistry, Vol. 280, Issue 12, pp. 12041-50, (2005) (PubMed).

  • 抗原
    CHEK2 (Checkpoint Kinase 2 (CHEK2))
    别名
    CHK2 (CHEK2 产品)
    别名
    CDS1 antibody, CHK2 antibody, HuCds1 antibody, LFS2 antibody, PP1425 antibody, RAD53 antibody, hCds1 antibody, fa66f08 antibody, wu:fa66f08 antibody, zgc:55865 antibody, Cds1 antibody, HUCDS1 antibody, Rad53 antibody, Chk2 antibody, cds1 antibody, chek2 antibody, chk2 antibody, hucds1 antibody, lfs2 antibody, pp1425 antibody, rad53 antibody, checkpoint kinase 2 antibody, serine/threonine-protein kinase chk2 antibody, checkpoint kinase 2 L homeolog antibody, CHEK2 antibody, chek2 antibody, Chek2 antibody, MCYG_07308 antibody, chek2.L antibody
    途径
    p53 Pathway, Apoptosis, Cell Division Cycle
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