电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

eIF4EBP1 抗体

EIF4EBP1 适用: 人 WB, ELISA Monoclonal unconjugated
产品编号 ABIN965483
发货至: 中国
  • 抗原 See all eIF4EBP1 (EIF4EBP1) 抗体
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    适用
    • 236
    • 165
    • 121
    • 21
    • 14
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    请咨询
    克隆类型
    • 237
    • 37
    单克隆
    标记
    • 115
    • 25
    • 18
    • 11
    • 10
    • 10
    • 10
    • 9
    • 9
    • 9
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This eIF4EBP1 antibody is un-conjugated
    应用范围
    • 216
    • 90
    • 86
    • 67
    • 66
    • 46
    • 30
    • 23
    • 16
    • 12
    • 10
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    Ni-NTA purified truncated recombinant 4EBP1 expressed in E. Coli strain BL21 (DE3).
    纯化方法
    Antibodies are purified by protein A affinity chromatography
    亚型
    IgG1
    Top Product
    Discover our top product EIF4EBP1 Primary Antibody
  • 应用备注
    Western Blot: 1: 500- 1: 1,000.
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 储存条件
    -20 °C
  • Fadden, Haystead, Lawrence: "Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes." in: The Journal of biological chemistry, Vol. 272, Issue 15, pp. 10240-7, (1997) (PubMed).

    Pause, Belsham, Gingras, Donzé, Lin, Lawrence, Sonenberg: "Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function." in: Nature, Vol. 371, Issue 6500, pp. 762-7, (1994) (PubMed).

  • 抗原
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    别名
    4E-BP1 (EIF4EBP1 产品)
    别名
    4E-BP1 antibody, 4EBP1 antibody, BP-1 antibody, PHAS-I antibody, 4e-bp1 antibody, AA959816 antibody, 153432_at antibody, 43-BP antibody, 4E-BP antibody, 4EBP antibody, 4e-bp antibody, 4eBP antibody, 4ebp antibody, BcDNA.HL08053 antibody, BcDNA:HL08053 antibody, CG8846 antibody, CT8705 antibody, Dm 4E-BP antibody, Dmel\\CG8846 antibody, Phas1 antibody, Thor/EIF4EBP antibody, anon-WO0172774.158 antibody, d4E-BP antibody, d4E-BP1 antibody, d4EBP antibody, d4e-bp antibody, d4eBP antibody, dthor antibody, eIF4E-BP antibody, l(2)06270 antibody, l(2)k07736 antibody, l(2)k13517 antibody, pp20 antibody, thor antibody, EIF4EBP1 antibody, fc04h09 antibody, wu:fc04h09 antibody, zgc:64137 antibody, eukaryotic translation initiation factor 4E binding protein 1 antibody, CG8846 gene product from transcript CG8846-RA antibody, EIF4EBP1 antibody, Eif4ebp1 antibody, Thor antibody, eif4ebp1 antibody
    背景
    4E-BP1(eukaryotic translation Initiation Factor 4E Binding Protein 1),also called ELF4EBP1/BP1/PHAS-I ,which is located on chromosome 8p12, with 118-amino acid protein (about 13kDa). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while(24kDa), the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.
    基因ID
    1978
    途径
    MAPK Pathway, PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Regulation of Cell Size, BCR Signaling
You are here:
客服