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MAP3K12 抗体 (C-Term)

MAP3K12 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB0976 unconjugated
产品编号 ABIN391319
发货至: 中国
  • 抗原 See all MAP3K12 抗体
    MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))
    抗原表位
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 828-859, C-Term
    适用
    • 30
    • 19
    • 12
    人, 小鼠
    宿主
    • 29
    • 2
    克隆类型
    • 29
    • 2
    多克隆
    标记
    • 13
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP3K12 antibody is un-conjugated
    应用范围
    • 18
    • 18
    • 11
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This ZPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-859 amino acids from the C-terminal region of human ZPK.
    克隆位点
    RB0976
    亚型
    Ig Fraction
    Top Product
    Discover our top product MAP3K12 Primary Antibody
  • 应用备注
    WB: 1:2000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Ye, Li, Yang, Xie, Yu, Ma, Zhu, Zhao, Lv: "MicroRNA-130a Targets MAP3K12 to Modulate Diabetic Endothelial Progenitor Cell Function." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 36, Issue 2, pp. 712-26, (2015) (PubMed).

    Couture, Blouin: "The DLK gene is a transcriptional target of PPAR?." in: The Biochemical journal, Vol. 438, Issue 1, pp. 93-101, (2011) (PubMed).

  • 抗原
    MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))
    别名
    ZPK (MAP3K12 产品)
    别名
    DLK antibody, MEKK12 antibody, MUK antibody, ZPK antibody, ZPKP1 antibody, PK antibody, Zpk antibody, zgc:77370 antibody, MGC151798 antibody, dlk antibody, map3k12 antibody, map3k12a antibody, mekk12 antibody, muk antibody, zpk antibody, zpkp1 antibody, DKFZp459K2433 antibody, map3k12-a antibody, map3k12-b antibody, map3k12b antibody, mitogen-activated protein kinase kinase kinase 12 antibody, mitogen activated protein kinase kinase kinase 12 antibody, mitogen-activated protein kinase kinase kinase 12 S homeolog antibody, mitogen-activated protein kinase kinase kinase 12 L homeolog antibody, MAP3K12 antibody, Map3k12 antibody, map3k12 antibody, map3k12.S antibody, map3k12.L antibody
    背景
    ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.
    分子量
    93219
    基因ID
    7786
    NCBI登录号
    NP_001180440, NP_006292
    UniProt
    Q12852
    途径
    MAPK Pathway
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