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MAP3K12 抗体 (C-Term)

The 兔 多克隆 anti-MAP3K12 antibody is suitable to detect MAP3K12 in samples from 人 和 小鼠. It has been validated for WB, IHC (p) 和 EIA.
产品编号 ABIN359408
发货至: 中国
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Quick Overview for MAP3K12 抗体 (C-Term) (ABIN359408)

抗原

See all MAP3K12 抗体
MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

适用

  • 30
  • 26
  • 12
人, 小鼠

宿主

  • 29
  • 9

克隆类型

  • 29
  • 9
多克隆

标记

  • 16
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MAP3K12 antibody is un-conjugated

应用范围

  • 21
  • 20
  • 18
  • 7
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    C-Term

    特异性

    This antibody detects MAP3K12 at C-term.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ZPK.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

    别名

    MAP3K12

    背景

    ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.Synonyms: Dual leucine zipper bearing kinase, Leucine-zipper protein kinase, MAPK-upstream kinase, Mitogen-activated protein kinase kinase kinase 12, Mixed lineage kinase

    分子量

    93188 Da

    基因ID

    7786, 9606

    UniProt

    Q12852

    途径

    MAPK Pathway
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