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MAP3K12 抗体 (C-Term)

There are 2+ publications for this product available. The 兔 多克隆 anti-MAP3K12 antibody is suitable to detect MAP3K12 in samples from 人 和 小鼠. It has been validated for WB 和 IHC (p).
产品编号 ABIN391319
发货至: 中国
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Quick Overview for MAP3K12 抗体 (C-Term) (ABIN391319)

抗原

See all MAP3K12 抗体
MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

适用

  • 30
  • 26
  • 12
人, 小鼠

宿主

  • 29
  • 9

克隆类型

  • 29
  • 9
多克隆

标记

  • 16
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MAP3K12 antibody is un-conjugated

应用范围

  • 21
  • 20
  • 18
  • 7
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB0976
  • 抗原表位

    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    AA 828-859, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This ZPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-859 amino acids from the C-terminal region of human ZPK.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Ye, Li, Yang, Xie, Yu, Ma, Zhu, Zhao, Lv: "MicroRNA-130a Targets MAP3K12 to Modulate Diabetic Endothelial Progenitor Cell Function." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 36, Issue 2, pp. 712-26, (2015) (PubMed).

    Couture, Blouin: "The DLK gene is a transcriptional target of PPAR?." in: The Biochemical journal, Vol. 438, Issue 1, pp. 93-101, (2011) (PubMed).

  • 抗原

    MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

    别名

    ZPK

    背景

    ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.

    分子量

    93219

    基因ID

    7786

    NCBI登录号

    NP_001180440, NP_006292

    UniProt

    Q12852

    途径

    MAPK Pathway
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