KHDRBS1 抗体 (N-Term)
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- 抗原 See all KHDRBS1 抗体
- KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 犬, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KHDRBS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- LPELMAEKDS LDPSFTHAMQ LLTAEIEKIQ KGDSKKDDEE NYLDLFSHKN
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against KHDRBS1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human KHDRBS1
- Top Product
- Discover our top product KHDRBS1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 443 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))
- 别名
- KHDRBS1 (KHDRBS1 产品)
- 别名
- Sam68 antibody, p62 antibody, p68 antibody, fj90g10 antibody, khdrbs1 antibody, wu:fa18g12 antibody, wu:fa56c01 antibody, wu:fc91b01 antibody, wu:fj90g10 antibody, zgc:113899 antibody, KHDRBS1 antibody, P62 antibody, khdrbs1l antibody, sb:cb97 antibody, wu:fb07d11 antibody, wu:fi43c05 antibody, zgc:85948 antibody, KH RNA binding domain containing, signal transduction associated 1 antibody, KH domain containing, RNA binding, signal transduction associated 1a antibody, KH domain containing, RNA binding, signal transduction associated 1 antibody, KH domain containing, RNA binding, signal transduction associated 1 S homeolog antibody, KH domain containing, RNA binding, signal transduction associated 1b antibody, KHDRBS1 antibody, khdrbs1a antibody, khdrbs1 antibody, Khdrbs1 antibody, khdrbs1.S antibody, khdrbs1b antibody
- 背景
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KHDRBS1 recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, KHDRBS1 functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. KHDRBS1 play a role in G2-M progression in the cell cycle. It represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. KHDRBS1 also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.
Alias Symbols: FLJ34027, Sam68, p62, p68
Protein Interaction Partner: UBC, LGR4, DROSHA, RPA3, RPA2, RPA1, RNF2, EZH2, BMI1, SUZ12, rev, APBB1, GAS7, WBP4, RASA1, SRC, CSK, PLCG1, PIK3R1, IRS1, CD81, TNFRSF1A, KHDRBS3, GPHN, RBM7, PIK3R3, HNRNPK, GRB2, EFEMP1, DHX9, DDX5, CRKL, CIRBP, ACTB, AZIN1, RBMX, AGO1, POT1, RBFOX2,
Protein Size: 443 - 分子量
- 48 kDa
- 基因ID
- 10657
- NCBI登录号
- NM_006559, NP_006550
- UniProt
- Q07666
- 途径
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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