(16 references)-
- 抗原 See all EGFR 抗体
- EGFR (Epidermal Growth Factor Receptor (EGFR))
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适用
- 人
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宿主
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绵羊
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克隆类型
- 多克隆
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标记
- This EGFR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunochromatography (IC)
- 交叉反应
- 小鼠, 大鼠, Turkey
- 纯化方法
- purified
- 免疫原
- EGFR antibody was raised in sheep using a synthetic 20 amino acid peptide of human EGFr representing a portion of the internal domain proximal to a phosphorylation region as the immunogen.
- Top Product
- Discover our top product EGFR Primary Antibody
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anti-Epidermal Growth Factor Receptor (EGFR) antibody
EGFR 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893), (Mutant) antibodyEGFR 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5G9B5 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibodyEGFR 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibodyEGFR 适用: 人, 小鼠, 大鼠, 猴, Pig, Cow, 小鸡, 犬, 马, 兔, 豚鼠, Avian, Cat, 驴, 山羊, Hamster, 绵羊 WB 宿主: 山羊 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (pSer1026) antibodyEGFR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (pSer695) antibodyEGFR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibodyEGFR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 960-1060) antibodyEGFR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 1021-1210) antibodyEGFR 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 1021-1210) antibodyEGFR 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: 10-50 µg/mL, IC: 25-100 µg/mL, IHC-P: 5 µg/mL, IP: 10-12 µg/mL, WB: 10-50 µg/mL
Optimal conditions should be determined by the investigator. - 限制
- 仅限研究用
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- 浓度
- Lot specific
- 缓冲液
- Protein G purified and supplied in PBS, pH 7.2.
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- -20 °C
- 储存方法
- Aliquot and store at -20 °C.
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: "Charcot-Marie-Tooth Type 2B: A New Phenotype Associated with a Novel RAB7A Mutation and Inhibited EGFR Degradation." in: Cells, Vol. 9, Issue 4, (2020) (PubMed).
: "ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes." in: The Journal of cell biology, Vol. 219, Issue 3, (2020) (PubMed).
: "Myosin VI and branched actin filaments mediate membrane constriction and fission of melanosomal tubule carriers." in: The Journal of cell biology, Vol. 217, Issue 8, pp. 2709-2726, (2019) (PubMed).
: "Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17." in: The Journal of cell biology, Vol. 217, Issue 8, pp. 2633-2645, (2019) (PubMed).
: "Sym004-induced EGFR elimination is associated with profound anti-tumor activity in EGFRvIII patient-derived glioblastoma models." in: Journal of neuro-oncology, Vol. 138, Issue 3, pp. 489-498, (2019) (PubMed).
: "Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation." in: Nature communications, Vol. 9, Issue 1, pp. 2932, (2018) (PubMed).
: "The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport." in: Oncotarget, Vol. 7, Issue 52, pp. 86871-86888, (2018) (PubMed).
: "LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning." in: The Journal of cell biology, Vol. 216, Issue 12, pp. 4199-4215, (2017) (PubMed).
: "Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy." in: eLife, Vol. 6, (2017) (PubMed).
: "Exosomes released by keratinocytes modulate melanocyte pigmentation." in: Nature communications, Vol. 6, pp. 7506, (2016) (PubMed).
: "Dennd3 functions as a guanine nucleotide exchange factor for small GTPase Rab12 in mouse embryonic fibroblasts." in: The Journal of biological chemistry, Vol. 289, Issue 20, pp. 13986-95, (2014) (PubMed).
: "CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor." in: Experimental cell research, Vol. 317, Issue 13, pp. 1804-16, (2011) (PubMed).
: "Cell adhesion and EGFR activation regulate EphA2 expression in cancer." in: Cellular signalling, Vol. 22, Issue 4, pp. 636-44, (2010) (PubMed).
: "Dysregulation of Ack1 inhibits down-regulation of the EGF receptor." in: Experimental cell research, Vol. 314, Issue 6, pp. 1292-300, (2008) (PubMed).
: "The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis." in: Experimental cell research, Vol. 313, Issue 8, pp. 1696-709, (2007) (PubMed).
: "Identification of 14-3-3zeta as an EGF receptor interacting protein." in: FEBS letters, Vol. 569, Issue 1-3, pp. 207-10, (2004) (PubMed).
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: "Charcot-Marie-Tooth Type 2B: A New Phenotype Associated with a Novel RAB7A Mutation and Inhibited EGFR Degradation." in: Cells, Vol. 9, Issue 4, (2020) (PubMed).
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- 抗原
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- 别名
- EGFR (EGFR 产品)
- 别名
- C-erb antibody, CG10079 antibody, D-EGFR antibody, D-Egf antibody, DEGFR antibody, DER antibody, DER flb antibody, DER/EGFR antibody, DER/faint little ball antibody, DER/top antibody, DER/torpedo antibody, DER1 antibody, DEgfr antibody, Degfr antibody, Der antibody, DmHD-33 antibody, Dmel\\CG10079 antibody, EFG-R antibody, EGF-R antibody, EGFR antibody, EGFr antibody, EGfr antibody, EK2-6 antibody, Egf antibody, Egf-r antibody, EgfR antibody, El antibody, Elp antibody, Elp-1 antibody, Elp-B1 antibody, Elp-B1RB1 antibody, HD-33 antibody, TOP antibody, Torpedo/DER antibody, Torpedo/Egfr antibody, c-erbB antibody, d-egf-r antibody, dEGFR antibody, dEGFR1 antibody, dEgfr antibody, der antibody, egfr antibody, flb antibody, l(2)05351 antibody, l(2)09261 antibody, l(2)57DEFa antibody, l(2)57EFa antibody, l(2)57Ea antibody, mor1 antibody, top antibody, top/DER antibody, top/flb antibody, torpedo/Egfr antibody, torpedo/egfr antibody, EGFR12 antibody, EGFR15 antibody, egfr1 antibody, Erbb2 antibody, ERBB antibody, ERBB1 antibody, HER1 antibody, PIG61 antibody, mENA antibody, ErbB-1 antibody, Errp antibody, 9030024J15Rik antibody, AI552599 antibody, Erbb antibody, Errb1 antibody, Wa5 antibody, wa-2 antibody, wa2 antibody, epidermal growth factor receptor antibody, Epidermal growth factor receptor antibody, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) antibody, EGFR antibody, Egfr antibody, egfra antibody, egfr1 antibody, LOC5564544 antibody
- 背景
- The epidermal growth factor receptor (EGFR) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. EGFR (epidermal growth factor receptor) exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor alpha (TGF alpha).
- 途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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