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BCL2 抗体 (B-Cell CLL/lymphoma 2) (PE)

Details for Product anti-BCL2 Antibody No. ABIN1105508, 供应商: Log in to see
抗原
  • Bcl-2
  • PPP1R50
  • bcl-2
  • AW986256
  • C430015F12Rik
  • D630044D05Rik
  • D830018M01Rik
  • BCL-2
  • Bcl2
  • B-cell CLL/lymphoma 2
  • B cell leukemia/lymphoma 2
  • B-cell leukemia/lymphoma 2
  • B-cell leukemia/lymphoma 2-like
  • B-cell CLL/lymphoma 2 protein
  • BCL2
  • Bcl2
  • LOC100224888
  • bcl2
  • LOC100359045
  • BCL-2
Alternatives
anti-大鼠 BCL2 抗体 for Immunofluorescence (fixed cells)
适用
人, 小鼠, 大鼠
1001
252
210
54
28
22
18
18
5
4
4
3
2
2
2
2
宿主
小鼠
549
517
19
6
2
2
2
克隆类型 (克隆位点)
单克隆 ()
标记
This BCL2 antibody is conjugated to PE
49
48
42
37
24
23
22
15
15
13
13
13
13
13
13
13
12
12
12
7
7
7
6
6
6
6
6
6
6
2
2
1
1
1
1
1
1
1
1
1
1
1
应用范围
Flow Cytometry (FACS)
791
374
361
309
307
297
228
191
170
81
40
15
14
13
12
11
9
4
3
2
1
1
1
1
1
1
1
Supplier
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免疫原 Recombinant rat Bcl-2beta
克隆位点 83-8B
亚型 IgG1
特异性 This antibody reacts with Bcl-2.
交叉反应 (详细) Species reactivity (tested):Human, mouse, rat
纯化方法 Protein A agarose
别名 Bcl-2 (BCL2 Antibody 摘要)
背景 The Bcl-2 related genes can inhibit (Bcl-XL and Mcl-1) or induce (Bax, Bcl-Xs, Bag and Bad) apoptosis in several systems. Bad was identified as a Bcl-2 interacting protein using a yeast two hybrid screening and λ expression cloning. It has homology to Bcl-2 within the Bcl-2 homolog domains 1 and 2 (BH1 and BH2). In mammalian cells, Bad selectively heterodimerizes with Bcl-XL as well as Bcl-2, but not with other Bcl-2 family members (Bax, Bcl-Xs, Mcl-1 and A1). When Bad heterodimerized with Bcl-XL, it displaced Bax from Bcl-XL and promoted cell death.Synonyms: Apoptosis regulator Bcl-2, B-Cell CLL/lymphoma 2, BCL2, Bcl-2 alpha
基因ID 24224
NCBI登录号 NP_058689
UniProt P49950
研究领域 Cancer, Apoptosis/Necrosis
途径 MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用
状态 Liquid
缓冲液 PBS, 0.09 % NaN3, 1 % BSA
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C
储存方法 Store at 2 - 8 °C.
厂商提供的图像
Flow Cytometry (FACS) image for anti-BCL2 抗体 (B-Cell CLL/lymphoma 2)  (PE) (ABIN1105508) anti-B-Cell CLL/lymphoma 2 (BCL2) antibody (PE)
背景 Gallatin, Weissman, Butcher: "A cell-surface molecule involved in organ-specific homing of lymphocytes. 1983." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 1, pp. 5-9, 2006 (PubMed).

Tanaka, Yoshimi, Maeyama, Hagimoto, Kuwano, Hara: "Resistance to Fas-mediated apoptosis in human lung fibroblast." in: The European respiratory journal, Vol. 20, Issue 2, pp. 359-68, 2002 (PubMed).