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抗Human PRKAB1 抗体:
抗Rat (Rattus) PRKAB1 抗体:
抗Mouse (Murine) PRKAB1 抗体:
Dog (Canine) Monoclonal PRKAB1 Primary Antibody for IF, WB - ABIN968185
Michell, Stapleton, Mitchelhill, House, Katsis, Witters, Kemp: Isoform-specific purification and substrate specificity of the 5'-AMP-activated protein kinase. in The Journal of biological chemistry 1996
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Salicylate activates the AMP-activated protein kinase (AMPK (显示 PRKAA2 抗体)) by binding at the A-769662 drug binding site on the AMPK (显示 PRKAA1 抗体) beta1-subunit
findings suggest that the reduced expression of AMPK (显示 PRKAA1 抗体)-beta1 confers lower AMPK (显示 PRKAA1 抗体) activity, which enhances the oncogenic capacity of advanced-stage ovarian cancer.
The effects of ethanol on AMPK (显示 PRKAA1 抗体) and PP2A (显示 PPP2R4 抗体) may result in activation of ChREBP (显示 MLXIPL 抗体), providing another potential mechanism for ethanol-induced hepatic steatosis.
Data indicate that a diet high in iron improves glucose tolerance by activating AMPK (显示 PRKAA1 抗体) through mechanisms that include deacetylation.
LKB1 (显示 STK11 抗体) controls IRS1 (显示 IRS1 抗体)-dependent adipogenesis via AMPK (显示 PRKAA1 抗体) in white adipose tissue.
Data indicate that except AMPK (显示 PRKAA1 抗体)-alpha1, expressions of the other five AMPK (显示 PRKAA1 抗体) subunits -alpha2, -beta1, -beta2, -gamma1 and -gamma2 are significantly higher in ovarian carcinomas.
Changes in translational control of mitochondrial proteins are signaled by the activation of AMPK and general control non-derepressible kinase 2 (GCN2), leading also to the activation of autophagy.
Phosphorylation levels of AMPK (显示 PRKAA1 抗体) and glycolysis were up-regulated to confer an advantage of survival for MERRF skin fibroblasts.
Adipose tissues of markedly obese insulin (显示 INS 抗体) resistant individuals uniformly show decreased AMPK (显示 PRKAA1 抗体) activity and increased oxidative stress compared with insulin (显示 INS 抗体) sensitive patients.
In breast cancer cells SESN2 (显示 SESN2 抗体) is associated with AMPK (显示 PRKAA1 抗体).
In lipid-laden macrophages, Ampk (显示 PRKAA1 抗体) activation decreased cholesterol content (foam cell formation) and increased cholesterol efflux to HDL (显示 HSD11B1 抗体) and apoA-I (显示 APOA1 抗体), effects that occurred in an Ampk (显示 PRKAA1 抗体) beta1-dependent manner.
AMPK (显示 PRKAA1 抗体) directly relaxes vascular smooth muscle cell by a decrease of [Ca(2 (显示 CA2 抗体)+)]i. This is achieved by calcium sequestration via SERCA (显示 ATP2A3 抗体) activation, as well as activation of BKCa (显示 KCNMA1 抗体) channels.
Norepinephrine increases the expression of PGC-1alpha (显示 PPARGC1A 抗体) in parallel with the activation of AMPK (显示 PRKAA1 抗体) signaling in mouse epididymal adipose tissue.
AMPK (显示 PRKAA1 抗体) beta1beta2 have a role in preventing myopathy due to loss of capillary density in nonpostural muscles
PPARbeta (显示 PPARD 抗体)/delta, but not PPARalpha (显示 PPARA 抗体), interacts with the exercise-inducible kinase AMP-activated protein kinase (AMPK (显示 PRKAA2 抗体)) to synergistically activate Ldhb (显示 LDHB 抗体) gene transcription by cooperating with myocyte enhancer factor 2A (MEF2A (显示 MEF2A 抗体)) in a PPARbeta (显示 PPARD 抗体)/delta ligand-independent manner
The aim of this study was to determine whether activation of AMPK (显示 PRKAA1 抗体) by acute renal ischemia influences the severity of renal ischemia-reperfusion injury.
AMPK (显示 PRKAA1 抗体) beta1 protects macrophages from inflammation under high lipid exposure from a high fat diet. beta1(-/-) macrophages displayed increased levels of diacylglycerol and markers of inflammation.
cisplatin-triggered activation of AMPK (显示 PRKAA1 抗体) and subsequent suppression of mTOR (显示 FRAP1 抗体) activity can induce an autophagic response that protects tumour cells from cisplatin-mediated apoptotic death
Phosphorylation of AMPK (显示 PRKAA1 抗体) by Ulk1 (显示 ULK1 抗体) represents a negative feedback circuit.
The extent of genetic polymorphisms in the promoter region of PRKAB1 gene was investigated in a sample of 811 Chinese indigenous bovine individuals.
Sequence analysis of 811 Chinese indigenous bovine individuals revealed 29 single nucleotide polymorphisms (SNPs) of bovine PRKAB1 gene.
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
5'-AMP-activated protein kinase subunit beta-1
, AMPK-activated protein kinase beta-1 subunit
, 5'AMP-activated protein kinase beta-1 non-catalytic subunit
, protein kinase, AMP-activated, beta 1 non-catalytic subunit
, AMP-activated protein kinase beta 1 non-catalytic subunit
, AMPK subunit beta-1
, 5'-AMP-activated protein kinase beta-1 subunit
, AMP-activated protein kinase beta subunit
, AMPK beta -1 chain
, AMPK beta 1
, protein kinase, AMP-activated, noncatalytic, beta-1
, 5'-AMP-activated protein kinase 40 kDa subunit
, 5'-AMP-activated protein kinase, beta subunit
, 5-AMP-activated protein kinase beta subunit
, AMPK beta-1 chain