anti-PFKFB3 (PFKFB3) 抗体产品概述

Full name:
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 抗体 (PFKFB3)
在www.antibodies-online.cn可供85 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) 抗体的15不同的供货商。 再加上,我们可以发PFKFB3 蛋白 (11)PFKFB3 试剂盒 (1)和数多这个蛋白质的别的产品。 总共104 PFKFB3产品已列进来了。
别名:
6-biphosphatase, 6-bisphosphatase, 6-phosphofructo-2-kinase/fructose-2, 6PF-2-K/Fru-2, E330010H22Rik, iPFK-2, IPFK2, PFK2, PFKFB3, uPFK-2, wu:fc31e01, zgc:73257
列出全部抗体 基因 基因ID UniProt
PFKFB3 5209 Q16875
PFKFB3 170768  
PFKFB3 117276 O35552

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抗Human PFKFB3 抗体:

抗Mouse (Murine) PFKFB3 抗体:

抗Rat (Rattus) PFKFB3 抗体:

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引用最多的anti-PFKFB3 抗体

  1. Human Polyclonal PFKFB3 Primary Antibody for EIA, IHC (p) - ABIN360653 : Navarro-Sabaté, Manzano, Riera, Rosa, Ventura, Bartrons: The human ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene (PFKFB3): promoter characterization and genomic structure. in Gene 2001 (PubMed)
    Show all 5 references for 360653

  2. Human Polyclonal PFKFB3 Primary Antibody for IHC (p), WB - ABIN392768 : Telang, Yalcin, Clem, Bucala, Lane, Eaton, Chesney: Ras transformation requires metabolic control by 6-phosphofructo-2-kinase. in Oncogene 2006 (PubMed)
    Show all 4 references for 392768

  3. Human Monoclonal PFKFB3 Primary Antibody for IP, ELISA - ABIN518808 : Bao, Mukai, Hishiki, Kubo, Ohmura, Sugiura, Matsuura, Nagahata, Hayakawa, Yamamoto, Fukuda, Saya, Suematsu, Minamishima: Energy management by enhanced glycolysis in G1-phase in human colon cancer cells in vitro and in vivo. in Molecular cancer research : MCR 2013 (PubMed)
    Show all 3 references for 518808

  4. Human Polyclonal PFKFB3 Primary Antibody for WB - ABIN518807 : Yamamoto, Takano, Ishiwata, Ohmura, Nagahata, Matsuura, Kamata, Sakamoto, Nakanishi, Kubo, Hishiki, Suematsu: Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway. in Nature communications 2014 (PubMed)

  5. Human Polyclonal PFKFB3 Primary Antibody for IF (p), IHC (p) - ABIN744728 : Fu, Shi, Westaway, Jhamandas: Bioenergetic mechanisms in astrocytes may contribute to amyloid plaque deposition and toxicity. in The Journal of biological chemistry 2015 (PubMed)

  6. Human Polyclonal PFKFB3 Primary Antibody for IP, WB - ABIN948248 : Mendoza, Pocceschi, Kong, Leeper, Caro, Limesand, Burd: Control of Glycolytic Flux by AMP-Activated Protein Kinase in Tumor Cells Adapted to Low pH. in Translational oncology 2012 (PubMed)

更多抗PFKFB3的相互作用对抗体

Zebrafish 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) interaction partners

  1. Study showed that endothelial cells (ECs)relied on glycolysis rather than on oxidative phosphorylation for ATP production and that loss of the glycolytic activator PFKFB3 in ECs impaired vessel formation.

Human 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) interaction partners

  1. This work has uncovered a novel function of the enzymes PFKFB3 and PFKFB4 (显示 PFKFB4 抗体) in ovarian cancer cells during mitotic arrest

  2. PFK-2 seems to be a strategic element that links NADPH oxidase (显示 NOX1 抗体) activation and glycolysis modulation, and, as such, is proposed as a potential therapeutic target in inflammatory diseases.

  3. Data suggest that hepatic glucokinase (显示 GCK 抗体) activity is regulated by reversible binding to specific inhibitor protein glucokinase regulatory protein (GKRP (显示 GCKR 抗体)) and by binding to activator proteins such as 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase (PFK2/FBP2 (显示 KHSRP 抗体)); changes in glucokinase (显示 GCK 抗体) expression and activity are associated with poorly controlled type 2 diabetes and nonalcoholic fatty liver disease. [REVIEW]

  4. PFKFB3 was a novel downstream substrate of mTOR (显示 FRAP1 抗体) signaling pathway as PFKFB3 level was augmented after knocking down TSC2 (显示 TSC2 抗体) in THP1 (显示 GLI2 抗体) and OCI-AML3 (显示 RUNX2 抗体) acute myeloid leukemia (显示 BCL11A 抗体) cells.

  5. Taken together, our study identifies PFKFB3 as a key TGFbeta1 (显示 TGFB1 抗体) effector protein that mediates TGFbeta1 (显示 TGFB1 抗体)'s effect on Snail (显示 SNAI1 抗体) expression, invasion, and glycolysis.

  6. we investigate the crosstalk between PFKFB3 and TIGAR (TP53-Induced Glycolysis and Apoptosis Regulator (显示 C12orf5 抗体)), a protein known to protect cells from oxidative stress. Our results show consistent TIGAR (显示 C12orf5 抗体) induction in HeLa cells in response to PFKFB3 knockdown

  7. Knockdown of PFKFB3 by siRNAs significantly inhibited the proliferation and migration abilities of gastric cancer cells. Our data suggest that PFKFB3 might be a potential biomarker for gastric cancer and anti-neoplastic targeting gene.

  8. The targeting of MCT1 (显示 CMA1 抗体) and PFKFB3 regulated cell proliferation.

  9. the novel role of PFKFB3 in induction of paclitaxel resistance by raising lactate production and activating TLR4 (显示 TLR4 抗体) signaling, was characterized.

  10. a novel role of PFKFB3 in glycolytic metabolism and ER stress of OA cartilage explants and chondrocytes

Mouse (Murine) 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3) interaction partners

  1. Blockage of glycolysis by targeting PFKFB3 alleviates sepsis-related acute lung injury via suppressing inflammation and apoptosis of alveolar epithelial cells.

  2. overexpression of PFKFB3 in HEK293 cells potentiated insulin (显示 INS 抗体)-dependent phosphorylation of Akt (显示 AKT1 抗体) and Akt (显示 AKT1 抗体) substrates

  3. Data show that inhibition of AMP (显示 TMPRSS5 抗体)-Activated kinase (AMPK (显示 PRKAA1 抗体)) or 6-phosphofructo-2-kinase-fructose-2,6-biphosphatase 3 (PFKFB3) results in enhanced cell death in mitosis.

  4. Shear stress-mediated repression of endothelial cell metabolism via KLF2 (显示 KLF2 抗体) and PFKFB3 controls endothelial cell phenotype.

  5. PFKFB3 is a promising target for the reduction of endothelial glycolysis and its related pathological angiogenesis

  6. PFKFB3/iPFK2 responds to re-feeding, which in turn stimulates hypothalamic glycolysis and decreases hypothalamic AMPK (显示 PRKAA1 抗体) phosphorylation and alters neuropeptide expression in a pattern that is associated with suppression of food intake.

  7. High-fat diet feeding stimulates intestine 6-phosphofructo-2-kinase expression and induces intestine inflammatory response.

  8. Study showed that endothelial cells (ECs)relied on glycolysis rather than on oxidative phosphorylation for ATP production and that loss of the glycolytic activator PFKFB3 in ECs impaired vessel formation.

  9. a unique role for PFKFB3/iPFK2 in adipocytes with regard to diet-induced inflammatory responses in both adipose and liver tissues.

  10. inducible PFKFB3 is required for increased growth, metabolic activity and is regulated through active JAK2 (显示 JAK2 抗体) and STAT5 (显示 STAT5A 抗体).

PFKFB3 抗原简介

Antigen Summary

Synthesis and degradation of fructose 2,6-bisphosphate (By similarity).

Alternative names and synonyms associated with PFKFB3

  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) 抗体
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (pfkfb3) 抗体
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PTRG_09894) 抗体
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (f263) 抗体
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PGTG_20206) 抗体
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (Tsp_06710) 抗体
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (Pfkfb3) 抗体
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (PFKFB4) 抗体
  • 6-biphosphatase 抗体
  • 6-bisphosphatase 抗体
  • 6-phosphofructo-2-kinase/fructose-2 抗体
  • 6PF-2-K/Fru-2 抗体
  • E330010H22Rik 抗体
  • iPFK-2 抗体
  • IPFK2 抗体
  • PFK2 抗体
  • PFKFB3 抗体
  • uPFK-2 抗体
  • wu:fc31e01 抗体
  • zgc:73257 抗体

Protein level used designations for PFKFB3

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 , 6-phosphofructo-2-kinase , fructose-2,6-biphosphatase 3 , 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 , 6PF-2-K/Fru-2,6-P2ASE brain/placenta-type isozyme , 6PF-2-K/Fru-2,6-P2ase 3 , PFK/FBPase 3 , 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3-like , 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase , 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase , 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme , fructose-6-phosphate,2-kinase/fructose-2, 6-bisphosphatase , iPFK-2 , inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase , renal carcinoma antigen NY-REN-56 , inducible 6-phosphofructo-2-kinase , 6PF-2-K/Fru-2,6-P2ASE brain-type isozyme , RB2K , 6-P2ase liver isozyme , 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase , 6PF-2-K/Fru-2,6-P2ase liver isozyme , PFK/FBPase

GENE ID SPECIES
418247 Gallus gallus
431861 Xenopus laevis
487139 Canis lupus familiaris
554477 Danio rerio
713062 Macaca mulatta
738397 Pan troglodytes
6348191 Pyrenophora tritici-repentis Pt-1C-BFP
100172898 Pongo abelii
100216216 Xenopus (Silurana) tropicalis
100350534 Oryctolagus cuniculus
100380757 Salmo salar
100414163 Callithrix jacchus
100464074 Ailuropoda melanoleuca
10535908 Puccinia graminis f. sp. tritici CRL 75-36-700-3
10911737 Trichinella spiralis
100070251 Equus caballus
5209 Homo sapiens
170768 Mus musculus
117276 Rattus norvegicus
407183 Bos taurus
415906 Gallus gallus
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