PEX5 抗体
(Peroxisomal Biogenesis Factor 5 (PEX5))
The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008].
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PEX5 抗体 by Grade
Find PEX5 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.
PEX5 抗体 by 适用
Find PEX5 抗体 for a variety of species such as anti-Mouse PEX5, anti-Human PEX5, anti-Rat PEX5. The species listed below are among those available. Click on a link to go to the corresponding products.
PEX5 抗体 by 应用范围
Find PEX5 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
PEX5 抗体 by 抗体来源
Find PEX5 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
PEX5 抗体 by 抗原表位
Find PEX5 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
PEX5 抗体 by 克隆形成能力
Find available monoclonal or polyclonal PEX5 抗体. Click on a link to go to the corresponding products.
PEX5 抗体 by 克隆
Find PEX5 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular PEX5 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN6145469
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (4)
Cat. No.
ABIN7261734
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Rat
Application
WB, IF, FACS
Validations
- (4)
Cat. No.
ABIN1500156
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7162986
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6264151
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN1500155
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7185408
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN3186406
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6743970
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6743971
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6145468
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
Cat. No.
ABIN6944504
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN6944505
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN6944517
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN6944503
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our PEX5 抗体
: "Mapping the cargo protein membrane translocation step into the PEX5 cycling pathway." in: The Journal of biological chemistry, Vol. 284, Issue 40, pp. 27243-51, (2009) (PubMed).: "Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse)." in: The American journal of pathology, Vol. 159, Issue 4, pp. 1477-94, (2001) (PubMed).
: "PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import." in: The Journal of cell biology, Vol. 147, Issue 4, pp. 761-74, (1999) (PubMed).
: "Recombinant human peroxisomal targeting signal receptor PEX5. Structural basis for interaction of PEX5 with PEX14." in: The Journal of biological chemistry, Vol. 274, Issue 9, pp. 5666-73, (1999) (PubMed).
: "A mouse model for Zellweger syndrome." in: Nature genetics, Vol. 17, Issue 1, pp. 49-57, (1997) (PubMed).
Aliases for PEX5 抗体
peroxisomal biogenesis factor 5 (pex5) 抗体peroxisomal biogenesis factor 5 (Pex5) 抗体
peroxisomal biogenesis factor 5 (PEX5) 抗体
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