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PFKFB3 抗体

PFKFB3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7262855
发货至: 中国
  • 抗原 See all PFKFB3 抗体
    PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
    适用
    • 78
    • 71
    • 60
    • 4
    • 3
    • 3
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 87
    • 5
    克隆类型
    • 82
    • 12
    多克隆
    标记
    • 40
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    • 4
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    • 1
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    This PFKFB3 antibody is un-conjugated
    应用范围
    • 67
    • 40
    • 40
    • 26
    • 17
    • 16
    • 10
    • 9
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    • 2
    • 1
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    Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human PFKFB3 (NP_004557.1).
    亚型
    IgG
    Top Product
    Discover our top product PFKFB3 Primary Antibody
  • 应用备注
    IHC 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
    别名
    PFKFB3 (PFKFB3 产品)
    别名
    IPFK2 antibody, PFK2 antibody, E330010H22Rik antibody, iPFK-2 antibody, uPFK-2 antibody, PFKFB3 antibody, zgc:73257 antibody, wu:fc31e01 antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 S homeolog antibody, PFKFB3 antibody, Pfkfb3 antibody, pfkfb3.S antibody, pfkfb3 antibody, PTRG_09894 antibody, Tsp_06710 antibody
    背景
    The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    基因ID
    5209
    UniProt
    Q16875
    途径
    AMPK Signaling, Regulation of Carbohydrate Metabolic Process
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