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PFKFB3 抗体

PFKFB3 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7248209
发货至: 中国
  • 抗原 See all PFKFB3 抗体
    PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
    适用
    • 78
    • 72
    • 60
    • 4
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    • 1
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    人, 大鼠
    宿主
    • 87
    • 5
    克隆类型
    • 82
    • 12
    多克隆
    标记
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    This PFKFB3 antibody is un-conjugated
    应用范围
    • 66
    • 40
    • 40
    • 25
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    Western Blotting (WB), ELISA
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human PFKFB3
    亚型
    IgG
    Top Product
    Discover our top product PFKFB3 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.9 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
    别名
    PFKFB3 (PFKFB3 产品)
    别名
    IPFK2 antibody, PFK2 antibody, E330010H22Rik antibody, iPFK-2 antibody, uPFK-2 antibody, PFKFB3 antibody, zgc:73257 antibody, wu:fc31e01 antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 S homeolog antibody, PFKFB3 antibody, Pfkfb3 antibody, pfkfb3.S antibody, pfkfb3 antibody, PTRG_09894 antibody, Tsp_06710 antibody
    背景
    The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 60 kDa

    UniProt
    Q16875
    途径
    AMPK Signaling, Regulation of Carbohydrate Metabolic Process
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