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UPF3B 蛋白

(UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
UPF3B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) UPF3B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) UPF3B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2735037)

UPF3B 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

UPF3B 蛋白 by Origin

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UPF3B 蛋白 by Source

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Popular UPF3B 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2735037
Quantity 20 μg
Datasheet Datasheet

Aliases for UPF3B 蛋白

UPF3B, regulator of nonsense mediated mRNA decay (UPF3B) 蛋白
UPF3 regulator of nonsense transcripts homolog B (yeast) (Upf3b) 蛋白
UPF3B, regulator of nonsense mediated mRNA decay (Upf3b) 蛋白
5730594O13Rik 蛋白
AI317193 蛋白
AW541158 蛋白
HUPF3B 蛋白
MRXS14 蛋白
RENT3B 蛋白
RGD1560264 蛋白
UPF3X 蛋白
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