UPF3B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
UPF3B
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
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- 抗原 See all UPF3B 蛋白
- UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This UPF3B protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human UPF3B / RENT3B (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product UPF3B 蛋白
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UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B) (AA 1-483) protein (Strep Tag)
Crystallography grade UPF3B 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
- 别名
- Upf3b,rent3b (UPF3B 产品)
- 别名
- HUPF3B Protein, MRXS14 Protein, RENT3B Protein, UPF3X Protein, 5730594O13Rik Protein, AI317193 Protein, AW541158 Protein, RGD1560264 Protein, UPF3B, regulator of nonsense mediated mRNA decay Protein, UPF3 regulator of nonsense transcripts homolog B (yeast) Protein, UPF3B Protein, Upf3b Protein
- 背景
- This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene.
- 分子量
- 56 kDa
- NCBI登录号
- NP_075386
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