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Siglece 抗体

(Sialic Acid Binding Ig-Like Lectin E (Siglece))
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
Siglec E 抗体 (ABIN1818480)

Siglece 适用: 小鼠 FACS, IP 宿主: 大鼠 Monoclonal 8D2 unconjugated

Siglec E 抗体 (FITC) (ABIN1818481)

Siglece 适用: 小鼠 FACS, IP 宿主: 大鼠 Monoclonal 8D2 FITC

Siglec E 抗体 (AA 20-355) (ABIN1982837)

Siglece 适用: 小鼠 IHC, WB 宿主: 绵羊 Polyclonal unconjugated

Siglece 抗体 by 适用

Find Siglece 抗体 for a variety of species such as anti-Mouse Siglece. The species listed below are among those available. Click on a link to go to the corresponding products.

Siglece 抗体 by 应用范围

Find Siglece 抗体 validated for a specific application such as FACS, IP, IHC, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Siglece 抗体 by 抗体来源

Find Siglece 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

Siglece 抗体 by 抗原表位

Find Siglece 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Siglece 抗体 by 克隆形成能力

Find available monoclonal or polyclonal Siglece 抗体. Click on a link to go to the corresponding products.

Siglece 抗体 by 克隆

Find Siglece 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

Siglece 抗体 by 标记

Find Siglece 抗体 with a specific conjugate such as FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Siglece 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application FACS, IP
Validations
  • (1)
Cat. No. ABIN1818480
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application FACS, IP
Validations
Cat. No. ABIN1818481
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Application IHC, WB
Validations
Cat. No. ABIN1982837
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Siglece 抗体

Smith, Deutzmann, Correa, Delaveris, Dhanasekaran, Dove, Sullivan, Wisnovsky, Stark, Pluvinage, Swaminathan, Riley, Rajan, Majeti, Felsher, Bertozzi: "MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 120, Issue 11, pp. e2215376120, (2023) (PubMed).

Dharmadhikari, Stolz, Hauke, Morgan, Varki, de Koning, Kelm, Maedler: "Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes." in: Scientific reports, Vol. 7, pp. 45319, (2017) (PubMed).

Wu, Ren, Chen: "Siglec-E Negatively Regulates the Activation of TLR4 by Controlling Its Endocytosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 8, pp. 3336-3347, (2016) (PubMed).

Aliases for Siglece 抗体

sialic acid binding Ig-like lectin E (Siglece) 抗体
Cd170 抗体
mSiglec-E 抗体
Siglec5 抗体
Siglec9 抗体
Siglec12 抗体
Siglecl1 抗体
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