anti-Hermansky-Pudlak Syndrome 1 (HPS1) 抗体

HPS1 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. 再加上,我们可以发HPS1 试剂盒 (12)HPS1 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
HPS1 3257 Q92902
HPS1 192236 O08983
HPS1    

antibodies-online.cn销售最多的anti-HPS1 抗体

Showing 10 out of 24 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 非结合性 ELISA, WB Figure 1: Western blot analysis using HPS1 mouse mAb against truncated HPS1 recombinant protein (1) and HPS1-hIgGFc transfected CHO-K1 cell lysate (2) . 100 μL Log in to see 24至29个工作日
¥11,113.07
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小鼠 非结合性 ELISA, WB   0.1 mL Log in to see 26至32个工作日
¥12,440.08
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非结合性 IHC, IHC (p) Immunohistochemistry: HPS1 Antibody [NBP2-31848] - melanoma Immunohistochemistry: HPS1 Antibody [NBP2-31848] - Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts. 0.1 mL Log in to see 28至35个工作日
¥3,591.24
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非结合性 IF, IHC, WB Immunohistochemistry of paraffin-embedded mouse stomach using HPS1 antibody at dilution of 1:100 (x40 lens). Immunohistochemistry of paraffin-embedded rat kidney using HPS1 antibody at dilution of 1:100 (x40 lens). 100 μL Log in to see 34至38个工作日
¥2,882.69
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小鼠 非结合性 WB 100 μL Log in to see 29至35个工作日
¥5,676.23
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小鼠 非结合性 EIA, WB 0.1 mL Log in to see 29至35个工作日
¥4,792.50
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非结合性 WB   100 μL Log in to see 5至7个工作日
¥20,898.73
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非结合性 ELISA, WB   50 μL Log in to see 7至10个工作日
¥2,864.83
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非结合性 IF, IHC, WB   50 μL Log in to see 29至35个工作日
¥4,028.97
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非结合性 ELISA, WB   150 μL Log in to see 7至10个工作日
¥6,876.25
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通过反应活性、应用领域、克隆类型和共轭标记 HPS1 抗体

特性 应用范围 宿主 克隆类型
Human ,
,
,
Mouse (Murine)


Rat (Rattus)


引用最多的anti-HPS1 抗体

  1. Human Monoclonal HPS1 Primary Antibody for ELISA, WB - ABIN969198 : Kobashi, Yoshida, Miyashita, Niki, Matsushima: Hermansky-Pudlak syndrome with interstitial pneumonia without mutation of HSP1 gene. in Internal medicine (Tokyo, Japan) 2005 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal HPS1 Primary Antibody for ELISA, WB - ABIN966298 : Nazarian, Falcón-Pérez, DellAngelica: Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 3 Pubmed References

更多抗HPS1的相互作用对抗体

Human Hermansky-Pudlak Syndrome 1 (HPS1) interaction partners

  1. BLOC-3 is a Rab32 (显示 RAB32 抗体) and Rab38 (显示 RAB38 抗体) guanine nucleotide exchange factor (显示 RASGRF1 抗体), with a specific function in the biogenesis of lysosome-related organelles. Silencing of the BLOC-3 subunits Hps1 and Hps4 (显示 HPS4 抗体) results in the mislocalization of Rab32 (显示 RAB32 抗体) and Rab38 (显示 RAB38 抗体).

  2. Seven mutations (six previously unreported) were described in the HPS1, HPS4 (显示 HPS4 抗体), and HPS5 (显示 HPS5 抗体) genes among Hermansky-Pudlak Syndrome patients of Mexican, Uruguayan, Honduran, Cuban, Venezuelan, and Salvadoran ancestries.

  3. a previously unreported missense mutation (G313S) at the 3' splice junction of exon 10 of Hermansky-Pudlak syndrome 1 protein resulted in activation of a cryptic intronic splice site causing an aberrantly spliced HPS1 mRNA

  4. Three different mutations in the HPS1 gene were found in the two families.

  5. Data show that recombinant HPS1-HPS4 (显示 HPS4 抗体) produced in insect cells can be efficiently isolated as a 1:1 heterodimer, and might function as a Rab9 (显示 RAB9A 抗体) effector in the biogenesis of lysosome-related organelles.

  6. Description of mutations in HPS genes that cause Hermansky-Pudlak syndrome (review)

  7. Four novel mutations were discovered and the diagnosis of HPS-1, available only on molecular grounds, has important prognostic and treatment implications.

  8. identification as a component of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organelles

  9. observations demonstrate that the Hermansky-Pudlak syndrome 1(HPS1) and HPS4 (显示 HPS4 抗体) proteins are components of a cytosolic complex that is involved in the biogenesis of lysosomal-related organelles

  10. Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) prot (显示 PLDN 抗体)eins HPS1 and HPS4.

Mouse (Murine) Hermansky-Pudlak Syndrome 1 (HPS1) interaction partners

  1. This may account for the tight correlation between Hps1 with Ptbp1 (显示 PTBP1 抗体) expression levels observed across mammalian tissues.

  2. Our study indicates that Ap3b1 (显示 AP3B1 抗体) gene play distinct roles in melanin production and tyrosinase (显示 TYR 抗体) distribution compared with Hps1 gene.

  3. The mouse genes for HPS, pale ear and pearl (显示 AP3B1 抗体), orthologous to the human HPS1 and HPS2 (ADTB3A (显示 AP3B1 抗体)) genes, copperate in production of platelet dense granules, melanosomes, and lysosomes.

  4. The coat-color phenotype of young homozygous double-mutant mice deficient in subunits of BLOC-3 (HPS1) and BLOC-1 (pallidin (显示 PLDN 抗体)) was indistinguishable from that of BLOC-1 (显示 PLDN 抗体) single mutants.

HPS1 抗原简介

蛋白简介

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome-related organelles complex (BLOC)-3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 1. Multiple transcript variants encoding distinct isoforms have been identified for this gene\; the full-length sequences of some of these have not been determined yet.

Gene names and symbols associated with HPS1

  • Hermansky-Pudlak syndrome 1 (HPS1) 抗体
  • Hermansky-Pudlak syndrome 1 (hps1) 抗体
  • Hermansky-Pudlak syndrome 1 homolog (human) (Hps1) 抗体
  • Hermansky-Pudlak syndrome 1 (Hps1) 抗体
  • 6030422N11Rik 抗体
  • BB405864 抗体
  • ep 抗体
  • Hps 抗体
  • HPS1 抗体
  • im:7143944 抗体
  • MGC123240 抗体
  • zgc:123240 抗体

Protein level used designations for HPS1

Hermansky-Pudlak syndrome 1 protein , Hermansky-Pudlak syndrome 1 , DKEYP-34H12.4 , Hermansky-Pudlak syndrome 1 protein homolog , Hermansky-Pudlak syndrome protein homolog , pale ear

GENE ID SPECIES
3257 Homo sapiens
280819 Bos taurus
429879 Gallus gallus
563067 Danio rerio
100021072 Monodelphis domestica
100070620 Equus caballus
192236 Mus musculus
100723233 Cavia porcellus
101110375 Ovis aries
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