anti-Hect Domain and RLD 5 (HERC5) 抗体

HERC5 is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. 再加上,我们可以发Hect Domain and RLD 5 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
HERC5 51191 Q9UII4
HERC5 514373  
HERC5 100063774  

antibodies-online.cn销售最多的anti-Hect Domain and RLD 5 抗体

Showing 10 out of 14 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-HERC5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HT1080 cell lysate 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
Cow 非结合性 IHC, WB WB Suggested Anti-HERC5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
小鼠 非结合性 ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL Log in to see 29至34个工作日
¥2,071.99
详细
非结合性 ELISA, WB 50 μg Log in to see 24至29个工作日
¥4,312.06
详细
Cow 非结合性 IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 29至35个工作日
¥6,705.77
详细
非结合性 WB HERC5 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 24至29个工作日
¥11,910.48
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非结合性 WB HERC5 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 24至29个工作日
¥11,910.48
详细
非结合性 IHC, IHC (p) Immunohistochemistry-Paraffin: HERC5 Antibody [NBP1-91985] Staining of human testis shows strong cytoplasmic positivity in the spermatogonia. 0.1 mL Log in to see 28至35个工作日
¥3,591.24
详细
非结合性 ICC, IF, WB Western Blot: HERC5 Antibody [NBP1-58102] - Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysate Western Blot: HERC5 Antibody [NBP1-58102] - hek293 cell lysate at 1:1000. 100 μL Log in to see 26至33个工作日
¥3,655.56
详细
非结合性 IHC (p), WB   50 μg Log in to see 29至35个工作日
¥6,705.77
详细

通过反应活性、应用领域、克隆类型和共轭标记 HERC5 抗体

特性 应用范围 宿主 克隆类型
Human ,
,

Cow (Bovine)


Horse (Equine)


引用最多的anti-Hect Domain and RLD 5 抗体

  1. Human Polyclonal HERC5 Primary Antibody for ELISA, WB - ABIN565561 : Woods, Kelly, Hattlmann, Tong, Xu, Coleman, Quest, Smiley, Barr: Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag. in Retrovirology 2011 (PubMed)
    Show all 4 references for 565561

  2. Cow (Bovine) Polyclonal HERC5 Primary Antibody for WB - ABIN2774738 : Salon, Merdzhanova, Brambilla, Brambilla, Gazzeri, Eymin: E2F-1, Skp2 and cyclin E oncoproteins are upregulated and directly correlated in high-grade neuroendocrine lung tumors. in Oncogene 2007 (PubMed)

更多抗Hect Domain and RLD 5的相互作用对抗体

Human Hect Domain and RLD 5 (HERC5) interaction partners

  1. HERC5 plays a crucial role in HCC (显示 FAM126A 抗体) immune evasion and has clinical relevance as a reproducible prognostic marker for risk of tumor recurrence and survival in patients.

  2. The inhibitory effect of ISG15 (显示 ISG15 抗体) on HCV RNA replication does not require its conjugation to substrates by HERC5.

  3. vIRF1 association with HERC5 altered ISG15 (显示 ISG15 抗体) modification of cellular proteins, and knockdown of ISG15 (显示 ISG15 抗体) augmented reactivation of KSHV from latency.

  4. The study reports on the NMR solution structure of a G-quadruplex formed by the CEB1 DNA G-rich fragment d(AGGGGGGAGGGAGGGTGG), harboring several G-tracts including one with six continuous guanines.

  5. Results show that HERC5 gene may be involved in regulating the spread of non-small cell lung cancer tumors where the methylation of its promoter is correlated with number increase of disseminated tumor cells and metastases as well as survival decreased.

  6. Authors identified a second distinct mechanism by which HERC5 inhibits HIV-1 replication and demonstrate that HERC5 is evolving under strong positive selection.

  7. Data indicate that income was inversely related to smoking behavior, and paternally derived CEB1 mutations were dose dependently increased when the father smoked in the 6 mo before pregnancy, 0.21 vs. 0.05 in smoking and nonsmoking fathers, respectively.

  8. The E3 ligase activity of HERC5 was required for blocking HIV-1 Gag particle production and correlated with the post-translational modification of Gag with ISG15 (显示 ISG15 抗体).

  9. This study characterizes HERC5 as a positive regulator of innate antiviral responses, and show that it sustains IRF3 (显示 IRF3 抗体) activation via a novel posttranslational modification, ISG15 (显示 ISG15 抗体)-ylation.

  10. Data show that HERC5, a functionally active HECT ubiquitin ligase, exhibits a tightly controlled cytosolic level under inflammatory conditions in endothelial cells.

Hect Domain and RLD 5 (HERC5) 抗原简介

蛋白简介

This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.

Gene names and symbols associated with HERC5

  • hect domain and RLD 5 (HERC5) 抗体
  • HECT and RLD domain containing E3 ubiquitin protein ligase 5 (HERC5) 抗体
  • CEB1 抗体
  • CEBP1 抗体
  • HERC5 抗体

Protein level used designations for HERC5

E3 ISG15--protein ligase HERC5 , hect domain and RLD 5 , probable E3 ubiquitin-protein ligase HERC5-like , HECT domain and RCC1-like domain-containing protein 5 , cyclin-E-binding protein 1 , probable E3 ubiquitin-protein ligase HERC5

GENE ID SPECIES
514373 Bos taurus
461369 Pan troglodytes
478474 Canis lupus familiaris
100063774 Equus caballus
100410536 Callithrix jacchus
100438710 Pongo abelii
100480303 Ailuropoda melanoleuca
100584608 Nomascus leucogenys
51191 Homo sapiens
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