HERC5 抗体 (Middle Region)
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北京 101111
Quick Overview for HERC5 抗体 (Middle Region) (ABIN2774739)
抗原
See all HERC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- HERC5 Antibody - middle region
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序列
- FHPEELKDVI VGNTDYDWKT FEKNARYEPG YNSSHPTIVM FWKAFHKLTL
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预测反应
- Cow: 79%, Horse: 79%, Human: 100%, Pig: 79%, Rabbit: 86%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against HERC5. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HERC5
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anti-Hect Domain and RLD 5 (HERC5) (AA 153-284) antibody
HERC5 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 915-1024) antibodyHERC5 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 287-336) antibodyHERC5 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 900-949) antibodyHERC5 适用: 人, Cow, 马, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (N-Term) antibodyHERC5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) antibodyHERC5 适用: 人 WB 宿主: 小鼠 Monoclonal 24GB15885 unconjugated
anti-Hect Domain and RLD 5 (HERC5) antibodyHERC5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 793-1024) antibodyHERC5 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (N-Term) antibodyHERC5 适用: 人, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43213-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- HERC5 (Hect Domain and RLD 5 (HERC5))
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别名
- HERC5
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背景
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Background Information: HERC5 is a member of the HERC family of ubiquitin ligases.It contains a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulates expression of HERC5 protein in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
Gene Name: HECT and RLD domain containing E3 ubiquitin protein ligase 5
Alternative Symbols: CEB1, CEBP1
Protein Name: E3 ISG15--protein ligase HERC5
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分子量
- 117kDa
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基因ID
- 51191
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NCBI登录号
- NP_057407
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UniProt
- Q69G20
抗原
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