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- 抗原 See all HERC5 抗体
- HERC5 (Hect Domain and RLD 5 (HERC5))
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抗原表位
- AA 153-284
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HERC5 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human E3 ISG15--protein ligase HERC5 protein (153-284AA)
- 亚型
- IgG
- Top Product
- Discover our top product HERC5 Primary Antibody
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anti-Hect Domain and RLD 5 (HERC5) (Middle Region) antibody
HERC5 适用: 人, Cow, 大鼠, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 915-1024) antibodyHERC5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 287-336) antibodyHERC5 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 900-949) antibodyHERC5 适用: 人, Cow, 马, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 360-700) antibodyHERC5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (N-Term) antibodyHERC5 适用: 人, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- HERC5 (Hect Domain and RLD 5 (HERC5))
- 别名
- HERC5 (HERC5 产品)
- 别名
- HERC5 antibody, CEB1 antibody, CEBP1 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 5 antibody, hect domain and RLD 5 antibody, HERC5 antibody
- 背景
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Background: Major E3 ligase for ISG15 conjugation. Acts as a positive regulator of innate antiviral response in cells induced by interferon. Functions as part of the ISGylation machinery that recognizes target proteins in a broad and relatively non-specific manner. Catalyzes ISGylation of IRF3 which results in sustained activation, it attenuates IRF3-PIN1 interaction, which antagonizes IRF3 ubiquitination and degradation, and boosts the antiviral response. Catalyzes ISGylation of influenza A viral NS1 which attenuates virulence, ISGylated NS1 fails to form homodimers and thus to interact with its RNA targets. Catalyzes ISGylation of papillomavirus type 16 L1 protein which results in dominant-negative effect on virus infectivity. Physically associated with polyribosomes, broadly modifies newly synthesized proteins in a cotranslational manner. In an interferon-stimulated cell, newly translated viral proteins are primary targets of ISG15.
Aliases: CEB1 antibody, CEBP1 antibody, Cyclin E binding protein 1 antibody, Cyclin-E-binding protein 1 antibody, E3 ISG15--protein ligase HERC5 antibody, HECT domain and RCC1 like domain containing protein 5 antibody, HECT domain and RCC1-like domain-containing protein 5 antibody, Hect domain and RLD 5 antibody, HECT E3 ubiquitin ligase antibody, HERC5 antibody, HERC5_HUMAN antibody, Herc6 antibody
- UniProt
- Q9UII4
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