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- 抗原 See all HERC5 抗体
- HERC5 (Hect Domain and RLD 5 (HERC5))
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抗原表位
- N-Term
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适用
- 人, Cow, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HERC5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- CLVAELVGYR VTQIACGRWH TLAYVSDLGK VFSFGSGKDG QLGNGGTRDQ
- 预测反应
- Cow: 86%, Dog: 79%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against HERC5. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HERC5
- Top Product
- Discover our top product HERC5 Primary Antibody
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anti-Hect Domain and RLD 5 (HERC5) (Middle Region) antibody
HERC5 适用: 人, Cow, 大鼠, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 153-284) antibodyHERC5 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 915-1024) antibodyHERC5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 287-336) antibodyHERC5 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 900-949) antibodyHERC5 适用: 人, Cow, 马, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hect Domain and RLD 5 (HERC5) (AA 360-700) antibodyHERC5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1024 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- HERC5 (Hect Domain and RLD 5 (HERC5))
- 别名
- HERC5 (HERC5 产品)
- 别名
- HERC5 antibody, CEB1 antibody, CEBP1 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 5 antibody, hect domain and RLD 5 antibody, HERC5 antibody
- 背景
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HERC5 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
Alias Symbols: CEB1, CEBP1
Protein Interaction Partner: UBC, SMAD4, UBE2D1, gag, ISG15, TXNRD1, IRF3, HSPA8, CTNNB1, HERC5, SIRT7, STK38, PITX2, ERCC2, CCND1, CCNE1, CCNB1, CCNA2, NME2, CDKN1A,
Protein Size: 1024 - 分子量
- 117 kDa
- 基因ID
- 51191
- NCBI登录号
- NM_016323, NP_057407
- UniProt
- Q9UII4
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