WRNIP1 产品
(Werner Helicase Interacting Protein 1 (WRNIP1))
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Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene. [provided by RefSeq, Jul 2012].
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Featured WRNIP1 Categories
WRNIP1 抗体
High quality antibodies with extensive validation data.
WRNIP1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
WRNIP1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended WRNIP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF
Validations
- (3)
Cat. No.
ABIN5590986
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Hamster, Human, Monkey, Mouse, Rat
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN6736353
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN129611
Quantity
100 μg
Datasheet
Datasheet
Recommended WRNIP1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1123032
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1123033
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1123034
Quantity
96 tests
Datasheet
Datasheet
Recommended WRNIP1 蛋白
Latest Publications for our WRNIP1 Products
: "Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 10, Issue 1, pp. 13-22, (2005) (PubMed).: "A novel protein interacts with the Werner's syndrome gene product physically and functionally." in: The Journal of biological chemistry, Vol. 276, Issue 23, pp. 20364-9, (2001) (PubMed).
Synonyms and alternative names related to WRNIP1
Werner helicase interacting protein 1 (WRNIP1), Werner helicase interacting protein 1 L homeolog (wrnip1.L), Werner helicase interacting protein 1 (wrnip1), ATPase WRNIP1 (EDI_075920), ATPase WRNIP1 (CpipJ_CPIJ017857), ATPase WRNIP1 (PITG_07216), ATPase WRNIP1 (VDBG_02914), Werner helicase interacting protein 1 (Wrnip1), ATPase WRNIP1 (PGTG_08805), 4833444L21Rik, bA420G6.2, RP11-420G6.2, WHIP, Whip, Wrnip, WRNIP1, wrnip1, zgc:85976Protein level used designations for WRNIP1
- ATPase WRNIP1
- Werner helicase interacting protein 1
- Werner helicase-interacting protein 1
- putative helicase RUVBL
- Werner helicasae interacting protein 1
- Werner syndrome homolog interacting protein
- werner helicase-interacting protein 1
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