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WRNIP1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

WRNIP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2715072
发货至: 中国
  • 抗原 See all WRNIP1 蛋白
    WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 2
    宿主
    • 1
    • 1
    资源
    • 1
    • 1
    HEK-293 Cells
    标记
    This WRNIP1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human ATPase WRNIP1 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product WRNIP1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))
    别名
    Atpase Wrnip1 (WRNIP1 产品)
    别名
    WRNIP1 Protein, wrnip1 Protein, RP11-420G6.2 Protein, WHIP Protein, bA420G6.2 Protein, zgc:85976 Protein, 4833444L21Rik Protein, Wrnip Protein, Whip Protein, Werner helicase interacting protein 1 Protein, Werner helicase interacting protein 1 L homeolog Protein, ATPase WRNIP1 Protein, WRNIP1 Protein, wrnip1.L Protein, wrnip1 Protein, EDI_075920 Protein, CpipJ_CPIJ017857 Protein, PITG_07216 Protein, VDBG_02914 Protein, Wrnip1 Protein, PGTG_08805 Protein
    背景
    Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene.
    分子量
    69.3 kDa
    NCBI登录号
    NP_569079
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