USP5 抗体
(Ubiquitin Specific Peptidase 5 (USP5))
Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010].
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Latest Publications for our USP5 抗体
: "Ubiquitin-specific peptidase 5, a target molecule of vialinin A, is a key molecule of TNF-α production in RBL-2H3 cells." in: PLoS ONE, Vol. 8, Issue 12, pp. e80931, (2013) (PubMed).: "Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini." in: The Journal of biological chemistry, Vol. 287, Issue 4, pp. 2317-27, (2012) (PubMed).
: "Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme." in: Chemistry & biology, Vol. 19, Issue 4, pp. 467-77, (2012) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "cDNA cloning of a human 100 kDa de-ubiquitinating enzyme: the 100 kDa human de-ubiquitinase belongs to the ubiquitin C-terminal hydrolase family 2 (UCH2)." in: FEBS letters, Vol. 376, Issue 3, pp. 233-7, (1996) (PubMed).
: "A human de-ubiquitinating enzyme with both isopeptidase and peptidase activities in vitro." in: FEBS letters, Vol. 359, Issue 1, pp. 73-7, (1995) (PubMed).
Aliases for USP5 抗体
ubiquitin specific peptidase 5 (USP5) 抗体ubiquitin carboxyl-terminal hydrolase 5 (CNH02890) 抗体
ubiquitin carboxyl-terminal hydrolase 5 (EHI_049940) 抗体
ubiquitin carboxyl-terminal hydrolase 5 (CC1G_12961) 抗体
ubiquitin carboxyl-terminal hydrolase 5 (MCYG_01862) 抗体
ubiquitin carboxyl-terminal hydrolase 5, putative (CGB_L3600C) 抗体
ubiquitin specific protease 5 (PY00546) 抗体
ubiquitin specific peptidase 5 (isopeptidase T) (Usp5) 抗体
ubiquitin specific peptidase 5 (Usp5) 抗体
AA407472 抗体
ISOT 抗体
ISOT-1 抗体
Ucht 抗体
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