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USP8 抗体

(Ubiquitin Specific Peptidase 8 (USP8))
Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. Deubiquitinates BIRC6/bruce and KIF23/MKLP1.
USP8 抗体 USP8 抗体 USP8 抗体 (ABIN2855692)

USP8 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated

USP8 抗体  (C-Term) USP8 抗体  (C-Term) USP8 抗体 (C-Term) (ABIN7174360)

USP8 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

USP8 抗体  (N-Term) USP8 抗体  (N-Term) USP8 抗体 (N-Term) (ABIN545113)

USP8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

USP8 抗体 by 适用

Find USP8 抗体 for a variety of species such as anti-Human USP8, anti-Mouse USP8, anti-Pig USP8. The species listed below are among those available. Click on a link to go to the corresponding products.

USP8 抗体 by 应用范围

Find USP8 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

USP8 抗体 by 抗体来源

Find USP8 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

USP8 抗体 by 抗原表位

Find USP8 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

USP8 抗体 by 克隆形成能力

Find available monoclonal or polyclonal USP8 抗体. Click on a link to go to the corresponding products.

USP8 抗体 by 克隆

Find USP8 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

USP8 抗体 by 标记

Find USP8 抗体 with a specific conjugate such as APC, Biotin, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular USP8 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p), IP, ICC
Validations
  • (4)
Cat. No. ABIN2855692
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7174360
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN545113
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN6150035
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (1)
Cat. No. ABIN7262975
Quantity 200 μL
Datasheet Datasheet
Reactivity Chicken, Human, Monkey
Application WB
Validations
  • (1)
Cat. No. ABIN6745387
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Pig
Application WB
Validations
  • (1)
Cat. No. ABIN6745282
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN1872156
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN388891
Quantity 400 μL
Datasheet Datasheet

Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2788008
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN357535
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IF
Validations
Cat. No. ABIN6760044
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IP
Validations
Cat. No. ABIN7452552
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP, IHC (fp)
Validations
Cat. No. ABIN7454885
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
Cat. No. ABIN2570139
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our USP8 抗体

Reincke, Sbiera, Hayakawa, Theodoropoulou, Osswald, Beuschlein, Meitinger, Mizuno-Yamasaki, Kawaguchi, Saeki, Tanaka, Wieland, Graf, Saeger, Ronchi, Allolio, Buchfelder, Strom, Fassnacht, Komada: "Mutations in the deubiquitinase gene USP8 cause Cushing's disease." in: Nature genetics, Vol. 47, Issue 1, pp. 31-8, (2014) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Soncini, Berdo, Draetta: "Ras-GAP SH3 domain binding protein (G3BP) is a modulator of USP10, a novel human ubiquitin specific protease." in: Oncogene, Vol. 20, Issue 29, pp. 3869-79, (2001) (PubMed).

Aliases for USP8 抗体

ubiquitin carboxyl-terminal hydrolase 8 (LOC9310109) 抗体
ubiquitin carboxyl-terminal hydrolase 8 (MGYG_00369) 抗体
ubiquitin specific peptidase 8 (USP8) 抗体
ubiquitin specific peptidase 8 (Usp8) 抗体
AI574262 抗体
AW557536 抗体
HumORF8 抗体
mKIAA0055 抗体
UBPY 抗体
Ubpy 抗体
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