USP34 抗体
(Ubiquitin Specific Peptidase 34 (USP34))
Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity).
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16 results
USP34
适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, 豚鼠, 马
WB, IHC, IF, IHC (p), IP
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our USP34 抗体
: "The ubiquitin specific protease USP34 protects the ubiquitin ligase gp78 from proteasomal degradation." in: Biochemical and biophysical research communications, Vol. 509, Issue 2, pp. 348-353, (2019) (PubMed).: "The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks." in: Nucleic acids research, Vol. 41, Issue 18, pp. 8572-80, (2013) (PubMed).
: "The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling." in: Molecular and cellular biology, Vol. 31, Issue 10, pp. 2053-65, (2011) (PubMed).
: "Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature." in: The American journal of pathology, Vol. 174, Issue 5, pp. 1650-62, (2009) (PubMed).
Aliases for USP34 抗体
ubiquitin specific peptidase 34 (Usp34) 抗体ubiquitin specific peptidase 34 (USP34) 抗体
ubiquitin specific peptidase 34 (usp34) 抗体
A530081C03Rik 抗体
Murr2 抗体
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