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PFDN4 inhibition resulted in an increase in cell growth and invasiveness in colorectal cancer cell lines.
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.
prefoldin subunit 4
, prefoldin 4
, Prefoldin subunit 4
, protein C-1