TYK2 抗体
(Tyrosine Kinase 2 (TYK2))
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| TYK2 抗体 (AA 581-719) (Fluoro647) | 人 | 兔 Polyclonal |
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| TYK2 抗体 (AA 581-719) (PE) | 人 | 兔 Polyclonal |
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| TYK2 抗体 (AA 1-1187) | 人 | 兔 Polyclonal |
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| TYK2 抗体 (AA 22-235) | 人 | 小鼠 Monoclonal |
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| TYK2 抗体 (AA 915-1173) | 人 | 小鼠 Monoclonal |
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| TYK2 抗体 (AA 680-1187) | 人 | 兔 Polyclonal |
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| TYK2 抗体 (AA 1052-1056) | 人, 小鼠 | 兔 Polyclonal |
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| TYK2 抗体 (AA 680-1176) | 人 | 兔 Polyclonal |
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| TYK2 抗体 (pTyr1054, Tyr1054) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| TYK2 抗体 (AA 286-372) (FITC) | 人 | 兔 Polyclonal |
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| TYK2 抗体 (Alexa Fluor 680) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| TYK2 抗体 (Alexa Fluor 555) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| TYK2 抗体 (Alexa Fluor 750) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| TYK2 抗体 (Alexa Fluor 647) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| TYK2 抗体 (Alexa Fluor 488) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| TYK2 抗体 (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| TYK2 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| TYK2 抗体 (AA 581-719) | 人 | 兔 Polyclonal |
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| TYK2 抗体 (pTyr1054) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| TYK2 抗体 (pTyr292) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Fluoro647
- 抗体亚型
- IgG
- 抗原表位
- AA 581-719
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- PE
- 抗体亚型
- IgG
- 抗原表位
- AA 581-719
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-1187
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- D3
- 标记
- unconjugated
- 抗原表位
- AA 22-235
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- D13
- 标记
- unconjugated
- 抗原表位
- AA 915-1173
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF/ICC (Immunofluorescence (fixed cells): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 680-1187
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1052-1056
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 680-1176
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Tyr1054, pTyr1054
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 286-372
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 581-719
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pTyr1054
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pTyr292
Latest Publications for our TYK2 抗体
: "Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 6, pp. 1585-97, (2014) (PubMed).
: "Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 12, pp. 7263-71, (2006) (PubMed).
: "Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 6, pp. 721-30, (2005) (PubMed).
: "TYK2 is a key regulator of the surveillance of B lymphoid tumors." in: The Journal of clinical investigation, Vol. 114, Issue 11, pp. 1650-8, (2004) (PubMed).
: "Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 2, pp. 1077-83, (2003) (PubMed).
: "The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression." in: The EMBO journal, Vol. 22, Issue 3, pp. 537-47, (2003) (PubMed).
: "Urokinase-induced migration of human vascular smooth muscle cells requires coupling of the small GTPases RhoA and Rac1 to the Tyk2/PI3-K signalling pathway." in: Thrombosis and haemostasis, Vol. 89, Issue 5, pp. 904-14, (2003) (PubMed).
: "Janus kinase 2 activation by the platelet-activating factor receptor (PAFR): roles of Tyk2 and PAFR C terminus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 7, pp. 3794-800, (2003) (PubMed).
: "Regulation of STAT protein synthesis by c-Cbl." in: Oncogene, Vol. 20, Issue 50, pp. 7326-33, (2001) (PubMed).
: "Interleukin-15 induces rapid tyrosine phosphorylation of STAT6 and the expression of interleukin-4 in mouse mast cells." in: The Journal of biological chemistry, Vol. 275, Issue 38, pp. 29331-7, (2000) (PubMed).
: "Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 12, pp. 7263-71, (2006) (PubMed).
: "Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 6, pp. 721-30, (2005) (PubMed).
: "TYK2 is a key regulator of the surveillance of B lymphoid tumors." in: The Journal of clinical investigation, Vol. 114, Issue 11, pp. 1650-8, (2004) (PubMed).
: "Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 2, pp. 1077-83, (2003) (PubMed).
: "The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression." in: The EMBO journal, Vol. 22, Issue 3, pp. 537-47, (2003) (PubMed).
: "Urokinase-induced migration of human vascular smooth muscle cells requires coupling of the small GTPases RhoA and Rac1 to the Tyk2/PI3-K signalling pathway." in: Thrombosis and haemostasis, Vol. 89, Issue 5, pp. 904-14, (2003) (PubMed).
: "Janus kinase 2 activation by the platelet-activating factor receptor (PAFR): roles of Tyk2 and PAFR C terminus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 7, pp. 3794-800, (2003) (PubMed).
: "Regulation of STAT protein synthesis by c-Cbl." in: Oncogene, Vol. 20, Issue 50, pp. 7326-33, (2001) (PubMed).
: "Interleukin-15 induces rapid tyrosine phosphorylation of STAT6 and the expression of interleukin-4 in mouse mast cells." in: The Journal of biological chemistry, Vol. 275, Issue 38, pp. 29331-7, (2000) (PubMed).
Aliases for TYK2 抗体
tyrosine kinase 2 (TYK2) 抗体tyrosine kinase 2 (Tyk2) 抗体
JTK1 抗体
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