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TYK2 抗体 (pTyr292)

The 兔 多克隆 anti-TYK2 antibody is suitable to detect TYK2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN8125503
发货至: 中国
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Quick Overview for TYK2 抗体 (pTyr292) (ABIN8125503)

抗原

See all TYK2 抗体
TYK2 (Tyrosine Kinase 2 (TYK2))

适用

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人, 小鼠, 大鼠

宿主

  • 89
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兔

克隆类型

  • 89
  • 13
多克隆

标记

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This TYK2 antibody is un-conjugated

应用范围

  • 63
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Western Blotting (WB), ELISA
  • 抗原表位

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    pTyr292

    原理

    Tyk 2 (Phospho Tyr292) Antibody

    特异性

    This antibody detects endogenous levels of Human Tyk 2 (Phospho Tyr292)

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized peptide derived from human Tyk 2 (Phospho Tyr292)

    亚型

    IgG
  • 应用备注

    WB 1:1000-2000 ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    TYK2 (Tyrosine Kinase 2 (TYK2))

    别名

    Tyk 2

    背景

    Synonyms: Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)

    Background: tyrosine kinase 2(TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],

    Gene Name: TYK2

    Protein Name: Tyk 2 (Phospho Tyr292)

    基因ID

    7297

    UniProt

    P29597

    途径

    JAK/STAT Signaling, Hepatitis C
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