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BCCIPbeta (显示 BCCIP 蛋白) interacts with the central basic region in S7 protein and regulates the extraribosomal distribution of S7.
RPS7 role in cell proliferation in the context of Hepatitis B virus-related hepatocellular carcinoma.SIRT7 trans-represses RPS7 gene in the presence of HBx protein.
Low expression of RPS7 is associated with colorectal cancer.
Knockdown of RPS7 resulted in increased expression of P85alpha, P110alpha (显示 PIK3CA 蛋白), and AKT2 (显示 AKT2 蛋白).
The study found two ribosomal proteins, RPS7 and RPL13A (显示 RPL13A 蛋白) that interact with the HMG (high-mobility group (显示 SSRP1 蛋白)) box (显示 SSRP1 蛋白) domain of SRY (显示 SRY 蛋白).
S7 binds to MDM2 (显示 MDM2 蛋白), in vitro and in vivo, and the interaction between MDM2 (显示 MDM2 蛋白) and S7 leads to modulation of MDM2 (显示 MDM2 蛋白)-p53 (显示 TP53 蛋白) binding by forming a ternary complex among MDM2 (显示 MDM2 蛋白), p53 (显示 TP53 蛋白) and S7.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
, ribosomal protein S7
, 40S ribosomal protein S7
, ribosomal protein S8 (rpS8B)
, 40S ribosomal protein S8
, ribosomal protein S8 (rpS8A)