TRAF3 抗体
(TNF Receptor-Associated Factor 3 (TRAF3))
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010].
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Latest Publications for our TRAF3 抗体
: "Chandipura virus changes cellular miRNome in human microglial cells." in: Journal of medical virology, (2019) (PubMed).: "TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 9, pp. 5084-96, (2000) (PubMed).
: "TRAF-3 mRNA splice-deletion variants encode isoforms that induce NF-kappaB activation." in: Molecular immunology, Vol. 36, Issue 10, pp. 647-58, (1999) (PubMed).
: "Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses." in: Immunity, Vol. 5, Issue 5, pp. 407-15, (1997) (PubMed).
: "Involvement of CRAF1, a relative of TRAF, in CD40 signaling." in: Science (New York, N.Y.), Vol. 267, Issue 5203, pp. 1494-8, (1995) (PubMed).
Aliases for TRAF3 抗体
TNF receptor associated factor 3 (TRAF3) 抗体TNF receptor-associated factor 3 (Traf3) 抗体
Tnf receptor-associated factor 3 (Traf3) 抗体
AI528849 抗体
amn 抗体
CAP-1 抗体
CAP1 抗体
CD40bp 抗体
CRAF1 抗体
IIAE5 抗体
LAP1 抗体
T-BAM 抗体
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