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TRAF3 抗体 (AA 240-289)

The 兔 多克隆 anti-TRAF3 antibody (ABIN1454010) specifically detects TRAF3 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1454010
发货至: 中国
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Quick Overview for TRAF3 抗体 (AA 240-289) (ABIN1454010)

抗原

See all TRAF3 抗体
TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

适用

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人, 小鼠

宿主

  • 83
  • 3
兔

克隆类型

  • 85
  • 1
多克隆

标记

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This TRAF3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 240-289

    原理

    TRAF3 Antibody

    特异性

    TRAF3 Polyclonal Antibody detects endogenous levels of TRAF3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human TRAF3. AA range:240-289

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

    别名

    TRAF3

    背景

    Synonyms: TRAF3, CAP1, CRAF1, TNF receptor-associated factor 3, CAP-1, CD40 receptor-associated factor 1, CRAF1, CD40-binding protein, CD40BP, LMP1-associated protein 1, LAP1

    Background: TNF receptor associated factor 3(TRAF3) Homo sapiens The protein encoded byThis gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010],

    Gene Name: TRAF3

    Protein Name: TNF receptor-associated factor 3

    分子量

    64 kDa

    基因ID

    7187

    OMIM

    601896

    UniProt

    Q13114

    途径

    NF-kappaB Signaling, Apoptosis, TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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