TRAF3 抗体 (AA 240-289)
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Quick Overview for TRAF3 抗体 (AA 240-289) (ABIN1454010)
抗原
See all TRAF3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 240-289
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原理
- TRAF3 Antibody
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特异性
- TRAF3 Polyclonal Antibody detects endogenous levels of TRAF3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human TRAF3. AA range:240-289
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))
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别名
- TRAF3
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背景
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Synonyms: TRAF3, CAP1, CRAF1, TNF receptor-associated factor 3, CAP-1, CD40 receptor-associated factor 1, CRAF1, CD40-binding protein, CD40BP, LMP1-associated protein 1, LAP1
Background: TNF receptor associated factor 3(TRAF3) Homo sapiens The protein encoded byThis gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010],
Gene Name: TRAF3
Protein Name: TNF receptor-associated factor 3
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分子量
- 64 kDa
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基因ID
- 7187
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OMIM
- 601896
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UniProt
- Q13114
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途径
- NF-kappaB Signaling, Apoptosis, TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
抗原
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