TPCN2 抗体
(Two Pore Segment Channel 2 (TPCN2))
This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.[provided by RefSeq, Dec 2009].
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Latest Publications for our TPCN2 抗体
: "Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes." in: eLife, Vol. 7, (2019) (PubMed).: "Characterization of Two-Pore Channel 2 by Nuclear Membrane Electrophysiology." in: Scientific reports, Vol. 6, pp. 20282, (2016) (PubMed).
: "NAADP and the two-pore channel protein 1 participate in the acrosome reaction in mammalian spermatozoa." in: Molecular biology of the cell, Vol. 25, Issue 6, pp. 948-64, (2014) (PubMed).
: "NAADP mobilizes calcium from acidic organelles through two-pore channels." in: Nature, Vol. 459, Issue 7246, pp. 596-600, (2009) (PubMed).
Aliases for TPCN2 抗体
two pore segment channel 2 (tpcn2) 抗体two pore segment channel 2 (Tpcn2) 抗体
two pore segment channel 2 (TPCN2) 抗体
two pore segment channel 2 L homeolog (tpcn2.L) 抗体
two pore calcium channel protein 2 (LOC100444397) 抗体
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