TNFSF4 蛋白
(Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells. [provided by RefSeq, Jul 2008].
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TNFSF4
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
AM, ADA, IA, ScA
TNFSF4
宿主: 小鼠
宿主: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS, AcA
Active
TNFSF4
宿主: 小鼠
宿主: Mammalian Cells
Recombinant
Greater than 95 % as determined by SDS-PAGE.
MALS verified
TNFSF4
宿主: 人
宿主: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
MALS verified
TNFSF4
宿主: 大鼠
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
MALS verified
TNFSF4
宿主: 兔
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
TNFSF4
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
WB, ELISA
Active
MALS verified
TNFSF4
宿主: 猕猴, Cynomolgus
宿主: HEK-293 Cells
Recombinant
90 %
Active
TNFSF4
宿主: 人
宿主: 人细胞
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
TNFSF4
宿主: 小鼠
宿主: 人细胞
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
Latest Publications for our TNFSF4 蛋白
: "Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist." in: Journal for immunotherapy of cancer, Vol. 9, Issue 1, (2021) (PubMed).
: "Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members." in: mAbs, Vol. 11, Issue 6, pp. 996-1011, (2020) (PubMed).
: "Agonist redirected checkpoint, PD1-Fc-OX40L, for cancer immunotherapy." in: Journal for immunotherapy of cancer, Vol. 6, Issue 1, pp. 149, (2018) (PubMed).
: "Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA." in: International immunology, Vol. 17, Issue 6, pp. 737-47, (2005) (PubMed).
: "Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members." in: mAbs, Vol. 11, Issue 6, pp. 996-1011, (2020) (PubMed).
: "Agonist redirected checkpoint, PD1-Fc-OX40L, for cancer immunotherapy." in: Journal for immunotherapy of cancer, Vol. 6, Issue 1, pp. 149, (2018) (PubMed).
: "Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA." in: International immunology, Vol. 17, Issue 6, pp. 737-47, (2005) (PubMed).
Aliases for TNFSF4 蛋白
TNF superfamily member 4 (TNFSF4) 蛋白tumor necrosis factor (ligand) superfamily, member 4 (TNFSF4) 蛋白
tumor necrosis factor (ligand) superfamily, member 4 (Tnfsf4) 蛋白
TNF superfamily member 4 (Tnfsf4) 蛋白
Ath-1 蛋白
Ath1 蛋白
CD134L 蛋白
CD252 蛋白
GP34 蛋白
gp34 蛋白
OX-40L 蛋白
OX4OL 蛋白
OX40L 蛋白
Ox40l 蛋白
TNFRSF4 蛋白
TNFSF4 蛋白
TXGP1 蛋白
Txgp1l 蛋白
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