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TKTL1 产品

(Transketolase-Like 1 (TKTL1))

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The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].

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Recommended TKTL1 抗体

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Cat. No. ABIN7339640
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Cat. No. ABIN7530378
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Recommended TKTL1 蛋白

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Latest Publications for our TKTL1 Products

Li, Yao, Xu, Qu, Li, Lin, Cao, Lin, Xu, Zhao, Zhao: "APC/CCDH1 synchronizes ribose-5-phosphate levels and DNA synthesis to cell cycle progression." in: Nature communications, Vol. 10, Issue 1, pp. 2502, (2019) (PubMed).

Tsaur, Thurn, Juengel, Oppermann, Nelson, Thomas, Bartsch, Oremek, Haferkamp, Rubenwolf, Blaheta: "Evaluation of TKTL1 as a biomarker in serum of prostate cancer patients." in: Central European journal of urology, Vol. 69, Issue 3, pp. 247-251, (2016) (PubMed).

Kämmerer, Gires, Pfetzer, Wiegering, Klement, Otto: "TKTL1 expression in human malign and benign cell lines." in: BMC cancer, Vol. 15, pp. 2, (2015) (PubMed).

Lucarelli, Galleggiante, Rutigliano, Sanguedolce, Cagiano, Bufo, Lastilla, Maiorano, Ribatti, Giglio, Serino, Vavallo, Bettocchi, Selvaggi, Battaglia, Ditonno: "Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma." in: Oncotarget, Vol. 6, Issue 15, pp. 13371-86, (2015) (PubMed).

Synonyms and alternative names related to TKTL1

transketolase-like 1 (Tktl1), transketolase like 1 (TKTL1), C79967, TKR, TKT2

Protein level used designations for TKTL1

  • TK 2
  • transketolase 2
  • transketolase-like protein 1
  • transketolase-2
  • transketolase-related protein
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