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use GPX4 and GPX7 as possible markers for improving HCC (显示 FAM126A 蛋白) diagnosis/prognosis.
SNPs most associated with Chemotherapy-induced peripheral neuropathy were in ATP-binding cassette sub-family C member 4 (ABCC4 (显示 ABCC4 蛋白)) gene.
Loss of glutathione peroxidase 7 promotes TNF-alpha (显示 TNF 蛋白)-induced NF-kappaB (显示 NFKB1 蛋白) activation in Barrett's carcinogenesis.
GPx7 promotes oxidative protein folding, directly utilizing Ero1alpha-generated hydrogen peroxide in the early secretory compartment.
tumour suppressor functions in esophageal adenocarcinomas and silenced by location-specific promoter DNA methylation (显示 HELLS 蛋白)
NPGPx protects against fat accumulation in mice and human via modulating ROS (显示 ROS1 蛋白)
GPx7 is an unusual CysGPx catalyzing the peroxidatic cycle by a one Cys (显示 DNAJC5 蛋白) mechanism in which GSH and PDI (显示 PADI1 蛋白) are alternative substrates.
NPGPx is essential for releasing excessive ER stress by enhancing GRP78 (显示 HSPA5 蛋白) chaperone activity to maintain physiological homeostasis.
GPx7 labeled as secreted glutathione peroxidase (显示 GPX1 蛋白), is actually endoplasmic reticulum-resident protein disulfide isomerase (显示 P4HB 蛋白) peroxidase
NPGPx plays an essential role in breast cancer cells in alleviating oxidative stress generated from polyunsaturated fatty acid metabolism
GPx7 is an unusual CysGPx catalyzing the peroxidatic cycle by a one Cys (显示 DNAJC5 蛋白) mechanism in which GSH and PDI (显示 PDIA3 蛋白) are alternative substrates.
Chloroplastic forms of Glutathione peroxidases regulate cellular photooxidative tolerance and immune responses. GPX1 and GPX7 have partially overlapping functions. [GPX7]
May constitute a glutathione peroxidase-like protective system against oxidative stresses (By similarity).
glutathione peroxidase 7
, Glutathione peroxidase 7
, glutathione peroxidase 6
, non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase