use GPX4 and GPX7 as possible markers for improving HCC diagnosis/prognosis.
SNPs most associated with Chemotherapy-induced peripheral neuropathy were in ATP-binding cassette sub-family C member 4 (ABCC4) gene.
Loss of glutathione peroxidase 7 promotes TNF-alpha-induced NF-kappaB activation in Barrett's carcinogenesis.
GPx7 promotes oxidative protein folding, directly utilizing Ero1alpha-generated hydrogen peroxide in the early secretory compartment.
tumour suppressor functions in esophageal adenocarcinomas and silenced by location-specific promoter DNA methylation
NPGPx protects against fat accumulation in mice and human via modulating ROS
GPx7 is an unusual CysGPx catalyzing the peroxidatic cycle by a one Cys mechanism in which GSH and PDI are alternative substrates.
NPGPx is essential for releasing excessive ER stress by enhancing GRP78 chaperone activity to maintain physiological homeostasis.
GPx7 labeled as secreted glutathione peroxidase, is actually endoplasmic reticulum-resident protein disulfide isomerase peroxidase
NPGPx plays an essential role in breast cancer cells in alleviating oxidative stress generated from polyunsaturated fatty acid metabolism
Chloroplastic forms of Glutathione peroxidases regulate cellular photooxidative tolerance and immune responses. GPX1 and GPX7 have partially overlapping functions. [GPX7]
May constitute a glutathione peroxidase-like protective system against oxidative stresses (By similarity).
glutathione peroxidase 7
, Glutathione peroxidase 7
, glutathione peroxidase 6
, non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase