TGS1 蛋白
(Trimethylguanosine Synthase 1 (TGS1))
Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation (By similarity).
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8 results
custom-made
TGS1
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
TGS1
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
TGS1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS
1 image
TGS1
宿主: Saccharomyces cerevisiae
宿主: 酵母菌
Recombinant
> 90 %
ELISA
Aliases for TGS1 蛋白
trimethylguanosine synthase 1 (TGS1) 蛋白trimethylguanosine synthase 1 (Tgs1) 蛋白
trimethylguanosine synthase 1 L homeolog (tgs1.L) 蛋白
D4Ertd800e 蛋白
NCOA6IP 蛋白
Ncoa6ip 蛋白
PIMT 蛋白
Pimt 蛋白
PIPMT 蛋白
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